Are we alive or dead if the brain is functioning organically but we are comatose? If we are
depressed on a bright, beautiful day, is it because our body's chemistry is out of kilter, or are
we warped in the soul? Is the heartsickness of unrequited love a result of an unsatisfied
emotional longing or a temporary chemical imbalance in the endocrine system? Do we
contemplate, and perhaps commit, suicide because some devil has possessed us or because a
molecular malfunction has occurred in our genes? HERBERT PARDES, M.D.