Lecture: (C) = Chasin (M) = Mowsh.	Date	Subject of Lecture	Recommended reading in Becker 5th ed. (B) and Purves 6th ed. (P) for Purves 5th ed, see '99 list	Recommended reading in Becker 4th ed. (B) and Purves 6th ed. (P) for Becker 3rd ed, see '99 list
1(C)	Tu 9/3/02	Introduction. Living things. Cells. Exponential growth.	B: Ch.1; Ch.2 p.17-31 P: Ch.1; Ch. 4 p.55-62	B: Ch.1; Ch.2 p.17-32 P: Ch.1; Ch. 4 p.55-62
2(C)	Th 9/5/02	Water. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers: 4 classes. Acids and bases. Sugars. Polysaccharides. Lipids. Amino acids. Stereo-isomers	B: Ch.3 p.41-44, 60-71 P: Ch.2 P:Ch.3 p.34-35, 43-46, 49-53	B: Ch.3 p.43-47, 61-72 P: Ch.2 P:Ch.3 p.34-35, 43-46, 49-53
3(C)	Tu 9/10/02	Protein structure. Peptide bonds. Alpha helix. Beta sheet. 3-D structure. Subunit interaction.	B: Ch.3 p.44-54 + Ch.2 p.31-37 P: Ch.3 p.36-42	B: Ch.3 p.47-55 + Ch.2 p.32-39 P: Ch.3 p.36-42
4(C)	Th 9/12 /02	Membrane proteins. Catalysis. Enzymes. Protein purification methods.	B: Ch.7 p.175-184 P: Ch.5 p.79-82; Ch.6 p.102-105	B: Ch.7 p.167-192 P: Ch.5 p.79-82; Ch.6 p.102-105
5(C)	Tu 9/17/02	Enzyme kinetics. Enzyme inhibitors. Feedback inhibition.	B: Ch.6 P: Ch.6 p.105-112	B: Ch.6 p.134-154,box6B P: Ch.6 p.105-112
6(C)	Th 9/19/02	Transfer of energy. ATP. Free energy. Introduction to energy metabolism.	B: Ch.5; Ch.13 p.368-372 P: Ch.6 p. 95-102	B: Ch.5.Ch.13 p.376-380 P: Ch.6 p. 95-102
7(C)	Tu 9/24/02	Glycolysis as a pathway in intermediary metabolism. Anaerobiosis.	B: Ch.13 p.372-386 P: Ch.7 p.113-121	B: Ch.13 p.380-393 P: Ch.7 p.113-121
Exam#1	Th 9/26/02	Covers topics actually covered in lectures 1 - 6 inclusive. Please note evening time for all.	5:40 - 7:40 PM and 7:30 - 9:30	See Exams page at course website
8(C)	Tu 10/1/02	Krebs (TCA) cycle. Electron transport. Oxidative phosphorylation. Mitochondria. Chemiosmosis.	B: Ch. 14 P: Ch.7 p.122-130	B: Ch. 14 P: Ch.7 p.122-130
No lect.	Th 10/3/02	C.U. Presidential Inaugural
9(C)	Th 10/8/02	Alternative energy sources. Biosynthetic pathways. Regulation of pathways.	B: Ch.6 p.147-151 Ch.13 p.386-392 P: Ch.7: p.130-134	B: Ch.6 p.151-157 Ch.13 p.393 - 400 P: Ch.7: p.130-134
10 (M)	Tu 10/10/02	DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication	B: Ch 3 p.54-60 (+Box3A) + Ch 16 p. 479-491 P: Ch 3 p. 47-49; Ch 11:198-205 +Fig.14.7	B: Ch 3 p. 55-63 + Ch 16 p. 488-501 P: Ch 3 p. 47-49; Ch 11:198-205 +Fig.14.7
11(M)	Tu 10/15/02	Details of DNA synthesis and PCR	B: Ch 17 p. 525-538 P: Ch 11 p. 206-end.	B: Ch 17 p. 535-554 P: Ch 11 p. 206-end.
12(M)	Th 10/17/02	Transcription & the central dogma	B: Ch 19 p. 623-640 + p. 654-end P: Ch 12 to p. 223	B: Ch 19 p. 634-651 + p. 665-666 P: Ch 12 to p. 223
13(M)	Tu 10/2202	Translation and the genetic code.	B:Ch 20 p. 660-674 P: Ch 12 p. 223-231	B:Ch 20 p. 670-682 P: Ch 12 p. 223-231
Exam #2	Th 10/24/02	Exam #2. Covers topics actually covered in lectures 7 - 12, inclusive.	5:40 - 7:40 PM and 7:30 - 9:30	See Exams page at course website
14(M)	Tu 10/29/02	Wrap up of translation; Mutation Regulation of protein synthesis in prokaryotes.	B: Ch 20 p. 674-676 P: Ch 12 p. 233 - end B: Ch 21 p. 692-701 P: Ch 13 p. 249-end	B: Ch 20 p. 682-686 P: Ch 12 p. 233 - end B: Ch 21 p. 701-711 P: Ch 13 p. 249-end
15(M)	Th 10/31/02	Bacterial and viral reproduction.	B: Ch 18 p.598-603 + Box 16A (p. 484-485) P: Ch 13 to p. 249	B: Ch 18 p .610-615 + Box 16A (p. 492-494) P: Ch 13 to p. 249
	Tu 11/5/02	Election day - no class
16(M)	Th 11/07/02	Restriction enzymes & recombinant DNA technology I. Gene cloning & forensics.	B: Ch. 18: p. 606-end; B: Ch. 16: 492--496 & Box 16-C. P: Ch. 17	B: Ch. 18: p. 618-629; B: Ch. 16: 501514 P: Ch. 17
17(M)	Tu 11/12/02	Recombinant DNA tech. II. Blots and probes. Discoveries about Eukaryotic gene/genome structure. Introns and exons.	Same as above. Also B: Ch. 19 p.647-653 P: Ch. 14 p. 265-270	Same as above. Also B: Ch. 19 p.660-665 P: Ch. 14 p. 265-270
18(M)	Th 11/14/02	Eukaryotic cell division I: Mitosis and the cell cycle (will do details of cell cycle and chromosome structure next term); meiosis	B: Ch 17 p. 523-525 & 544-554; Ch 18 p. 577-590. P: Ch 9	B: Ch 17 p. 533-535 & 554-564 P: Ch 9 p. 155-167
19(M)	Tu 11/19/02	Eukaryotic cell division II: Consequences of Meiosis -- sex determination, non- disjunction, life cycles & intro to genetics	Same as above.	B: Ch 18 p. 589-602 P: Ch 9 p. 167-end
Exam #3	Th 11/21/02	Exam #3: Covers topics actually covered in lectures 13-18, inclusive	5:40 - 7:40 PM and 7:30 - 9:30	See Exams page at course website
20(M)	Tu11/26/02	Eukaryotic genetics I: One gene at a time.	B: Ch 18 p. 590-595 P: Ch 10 p.176-188, 192-196 (skip dihybrid crosses for now)	B: Ch 18 p. 602-604 P: Ch 10 p.176-188, 192-196 (skip dihybrid crosses)
No lecture	Th 11/28/02	No class--Thanksgiving
21(M)	Tu 12/3/02	Eukaryotic genetics II: Genetic diseases, crosses with more than one gene at a time. Crossing over, linkage and mapping	B: Ch 18 p 595-598 P: Ch 10 p 188-193 + Ch 18 p 331-342, 346-end	B: Ch 18 p 604-610 P: Ch 10 p 188-193 + Ch 18 p 331-342, 346-end
22(M)	Th 12/5/02	Intro to Darwinian evolution, Population genetics and molecular evolution (last lecture)	P: Ch.21 & Ch. 24	P: Ch.21 & Ch. 24
Review session (M)	Th 12/12 &/or Tu 12/17	Review session (optional)	Times & Rooms TBA
Exam #4 (final)	Th 12/19/02 4-7 PM	Exam #4. EMPHASIZES LECTURES 19- 22, but can refer back to the entire course.	Please note the date & time and make travel arrangements accordingly.