C2005/F2401 '09 -- Outline for Lecture #19

Posted/last updated 11/18/09 03:22 PM

I. Introns & Exons -- Wrap up of Splicing

II. Intro to Eukaryotic cell division: How does one eukaryotic cell make two?

Problems caused by structure of eukaryotic genetic material -- more than one chromosome, chromosomes in nucleus, etc.

III. Basic Solution -- 2 different states of the nucleus and the DNA

        A. Chromatin -- interphase state (between divisions)

        B. Chromosomes -- state during division (mitosis)

IV. The Cell Cycle -- M, G1, S & G2

V. The Mitotic Chromosome Cycle -- Chromosomes, Chromatids & Centromeres. See handout 19B

VI. Mitosis -- what happens at each major stage? What are the products? See handout 19A

VII. Karyotypes -- pictures of the chromosomes, paired and arranged in descending order

    A. How you make karyotypes. See handout 19B.

    B. What you can tell from looking at normal karyotypes -- banding, ploidy (N, 2N, etc.), N, homologs, sister chromatids, autosomes, & sex chromosomes.

    C. What you learn from looking at abnormal karyotypes -- aneuploidy & rearrangements.

VIII.  Overview of Meiosis --  How does one multicellular organism, not just a cell, make two? See Handout 19C

    A. What is meiosis for?

    B. What happens to chromosomes during meiosis?

    C. What happens to DNA/cell (called "c")?

Next Time: Details of Meiosis & Comparisons to Mitosis (see 19A) , and then Life Cycles -- how do meiosis and mitosis fit together?