ln Lecture 8, page 12, 3rd line, you said, "Glu --->
...". What did you mean by coupling formation of ATP? I thought coupling usually
refers to making ADP in an exergonic rxn.
I cannot find this reference, as the page number depends on your printer. But, no,
coupling refers to two otherwise independent reactions that are obligatorily carried out
together by the enzyme. Thus when ATP is produced by substrate-level phosphorylation, it
is via coupled reactions producing ATP from ADP + Pi, as in the 2 relevant steps (7 and
10) in glycolysis. These are coupled reactions just like hexokinase (think of the
hexokinase reaction in reverse, still coupled).