Biology C2005/F2401 - 2012 Intro Bio

Schedule of Lectures, recommended readings, exams, and download links

Students with older editions of the texts can consult older reading lists and find the readings for the same topics. To study lecture material in advance you may access those from last year which are usually very similar.
See additional notes below.

Download codes:

LH : lecture notes in html
LP : lecture notes as pdf
O : outline

M : mp3 audio of lecture
W : WMA audio of lecture
Q : QuickTime movie of eve. lec. PPT
PP : PowerPoint used in lecture
H : Handouts used in lecture

Lecture notes, recording, etc. added as we go.

Lecture:
(C)hasin
(M)owsh.

Date

Subject of Lecture

Recommended reading in Becker 8th ed. (B) or Savada 9th ed. (S)

Downloads

1 (C)

Tu
9/4/12

Introduction. Living things. Cells. Exponential growth. Water.

B: Ch.1;Ch.2:18-32; Ch.4:75-79
S: Ch 1 + Ch 5.1+5.2

2 (C)

Th
9/6/12

Water contd. Strong and weak chemical bonds. Small vs. large molecules. Bio-polymers. Acids and bases. Sugars. Polysaccharides.

B: Ch.3: 46-47; 60-66
S: Ch.2; Ch 3.1, 3.3

3 (C)

Tu
9/11/12

Polysaccharides cont. Lipids. Phospholipids. Membranes.

B: Ch.3: 65-70; Ch7: 167-173
S: Ch. 3.4; Ch 6: 105-108

4 (C)

Th
9/13/12

Amino acids. Stereo-isomers. Protein structure. Peptide bonds. Small molecule separation methods.

B: Ch.3: 41-48; Ch.2: 21-22
S: Ch. 3.2

5 (C)

Tu
9/18/12

Alpha helix. Beta sheet. 3-D structure. Subunit interaction. Domains.

B: Ch. 3: 48-54
S: Ch. 3.2 again

6 (C)

Th
9/20/12

Prosthetic groups. Membrane proteins. Catalysis. Enzymes. Protein purification methods. Chemical kinetics.

B: Ch.7:161-162,179
S: Ch. 8:156-161

7 (C)

Tu
9/25/12

Enzyme kinetics. Enzyme inhibitors. Feedback inhibition. Free energy and the direction of chemical reactions. ATP hydrolysis.

B: Ch. 6; Ch.5
S: Ch. 8: 161-165; 148-155

yet

Exam #1

Th
9/27/12

Exam #1.
Covers topics actually covered in lectures 1 - 6 inclusive.
Note exams are not at morning class times.
Optional review session (questions answered) held at the morning class time and place

5:40 - 7:20 PM or 7:30 - 9:10M
See EXAM 1 INFO page for link to room and time assignments.
Email Paige Thompson
( [email protected] ) to request justified changes in exam room assignment

8 (C)

Tu
10/2/12

Glycolysis as a pathway in intermediary metabolism. Anaerobiosis. .

B: Ch.9: 224-238
S: Ch.9: 170-177

9 (C)

Th
10/4/12

Krebs (TCA) cycle. Electron transport. Oxidative phosphorylation. Alternative energy sources. Biosynthetic pathways.

B: Ch.10
S: Ch 7:150-157
Required: "Carbon" by P. Levi
optional skim: B:Ch.11/S:Ch.8

10 (M)

Tu
10/9/12
Drop deadline

DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication

B: Ch. 3:54-60 + Box 3A;Ch. 18:505-517
S: Ch. 4.1,
13.1 & 13.2 & fig. 14.8

11(M)

Th
10/11/12

Wrap up of DNA structure; Details of DNA synthesis

B: Ch. 19:551-567
S: Ch. 13.3 & 13.4

12 (M)

Tu
10/16/12

PCR
Transcription & the central dogma
(Both lectures 11 and 12 will be presented on this day.)

B: Box 19A
S: Ch. 13.5
B: Ch. 21: 645-660 & 674-end.
S: Ch. 14.1 -14.3

Exam #2

Th
10/18/12

Exam #2. Covers topics of lectures 7 - 11 inclusive. Optional review session (questions answered) at morning class time and place.

5:40 - 7:20 PM and
7:30 - 9:10PM **
Room(s) TBA

13 (M)

Tu
10/23/12

Wrap up of transcription; Intro to Translation and the genetic code.

B: Ch. 22 to p. 693
S: Ch. 14.5 (14.6 next term)

14 (M)

Th
10/25/12

Translation & the genetic code, cont.; (will finish in #15 if necessary)

See previous lect; For mutation:
B: Ch. 22: 693-695
S: Ch. 15.1

15 (M)

moved to Th 11/1/12

Mutation & Regulation of protein synthesis in prokaryotes.

B: Ch. 23 to p. 718.
S: Ch. 16.2

16 (M)

11/2 & 11/8

Postponed from orig. date. Given 2X; on Fri 11/2/12 & Th 11/8
Bacterial and viral reproduction.

B: Ch. 20: 620-624 & Box 18A (p.508-509)
S: Ch. 12.6 & 16.1

Tu
11/6/12

ELECTION DAY - NO CLASS

17 (M)

Th
11/8/12

Recombinant DNA technology I. Restriction enzymes & forensics. Blots and probes.

B: Ch. 18: 518-520
& Boxes 18B & 18C
S: Ch. 15.2

18 (M)

Tu
11/13/12

Recombinant DNA tech. II. Molecular cloning;

Discoveries about Eukaryotic gene/genome structure. Introns and exons.

B: Ch 20: 628-end.
S. Ch. 18
B: Ch. 21: 669-674.
S: Ch. 14.4

Exam #3

Th
11/15/12
P/F deadline

Exam #3: Covers topics of lectures 12-17 (See Exam 3 Page for details). Optional review session (questions answered) at morning class time and place.

5:40 - 7:20PM and
7:30 - 9:10M **
Room(s) TBA

19 (M)

Tu
11/20/12

Wrap up of Recombinant DNA & Eukaryotic Gene Structure; Intro to Eukaryotic cell division I: Mitosis and the cell cycle (details of cell cycle and chromosome structure next term)

B: Ch. 19: 549-551 & 571-580.
S: Ch. 11.1-11.3

Th
11/22/12

Thanksgiving holiday

20 (M)

Tu
11/27/12

Eukaryotic cell division II: Mitosis & Meiosis. Next time: The consequences -- sex determination, non- disjunction, life cycles and intro to simple inheritance (if time).

B: Ch. 20: to p 612.
S: Ch. 11.4-11.5

21(M)

Th
11/29/12

Eukaryotic Genetics I: One gene at a time. Crosses & Genetic diseases.

B: Ch. 20: 612-618
S: Ch. 12.1, 12.2, & 12.4 pp. 256-259. (skip dihybrid crosses for now)

22 (M)

Tu
12/4/12

Crosses with more than one gene at a time. Intro to Linkage and mapping

B: Ch. 20: 618-620
S: Ch. 12.3 to 12.4; Ch. 15.3-15.6

23 (M)

Th
12/6/12

Wrap up of linkage; Darwinian evolution, population genetics and molecular evolution

S: Ch. 1.1 & 1.2; Ch. 21 & Ch. 24

Review (M)

Thursday 12/13

Review Sessions -- Q & A with Dr. M. Usual Class Times, but both sessions in 309 Havemeyer.

FINAL EXAM

Tu
12/18/12
4:10-7:00
&7:10-10

Exam #4. EMPHASIZES LECTURES 18 - 23, but will refer back to entire course.
Important: This is not the usual date & time for a class that meets Tu-Th at 10:35 or 5:40. Please take this into account when buying tickets to go home.

Rooms TBA

Exams are designed to be completed in 75 minutes. Students with a class conflict at 5:40 exam may take the exam at 7:30 (requires permission including proof of class conflict: CU printout of schedule). Students with class conflicts at 5:40 AND 7:30 should contact Paige Thompson ([email protected]) to search for an alternative.

If you have trouble getting the m4a file to open in QuickTime by clicking in your browser, or the display is too small, save it to a folder on your computer, open QuickTime Player, and then open the lecX_10.m4a file in QuickTime. QuickTime Player can be downloaded here (iTunes not needed). You may need v. 7.6.6 or later.

Web lectures and outlines are usually provided by the early morning hours before live lectures 1-9. Materials for lectures 10-23 are usually ready by 9 pm the night before. There are links to figures in an older Purves (Savada) text embedded in the lectures. Answered questions posed by students in previous years are also provided: follow the red Q&A links to see a more complete explanation; the green Q&A links expand upon a subject.

Savada and Purves refer to the same basic text: Sadava is the first author from the 8th edition on, Purves was the first author of editions 1-7.

Note: Regarding exams, students are responsible for the material presented in lectures, the Web lectures, the handouts, and the problems. The texts should be used to help understand the lectures; you are not responsible for any topics or information that is in the text but not in the live and Web lectures, handouts, or problems. Additional material is sometimes provided in the Web lectures in the form of links to outside sources and links to additional pictures and diagrams. You are only responsible for the links to the handouts, hard copies of which are provided in class.