Biology C2005/F2401 - 2015 Intro Bio Midterm dates will be the following Thursdays: 10/1, 10/22, & 11/19.

Schedule of Lectures, recommended readings, exams, and download links 
Students with older editions of the texts can consult older reading lists and find the readings for the same topics.
To study lecture material in advance you may access those from last year which are usually very similar. 
See additional notes below.

    ++Download codes:
LH, lecture notes in html;
LP, lecture notes as pdf;
O, outline
M,  mp3 audio of lecture

W, WMA audio of lecture;
PP, PowerPoint
PPp, Powerpoint as pdf (some loss)
NarPP, PowerPoint used in lecture, with  narration (sync'd audio)

 For readings:
B = Becker 8th ed.  
S = Savada 10th ed. 
(9th ed. of S is in paren. if different.) 

Lecture notes, recording, etc. added as we go.
 
Lecture:
(C)hasin
(M)owsh.		  Date  Subject of Lecture Recommended reading in Becker or Sadava

Downloads
 
1 (C) Tu
9/8/15		 Introduction. Living things. Cells. Exponential growth. B: Ch.1;Ch.2:18-32; Ch.4:75-79
S: Ch 1 + Ch 5.1+5.2		 LH LP   M W Pp PPp Nar PP
2  (C) Th
9/10/15		 Water. Strong and weak chemical bonds. Functional groups. Small vs. large molecules. Bio-polymers. Acids and bases.  B: Ch.3: 46-47; 60-66
S: Ch.2; Ch 3.1, 3.3 		LH LP   M W Pp PPp

Nar
PP
3 (C) Tu
9/15/15		 Sugars. Polysaccharides. Lipids: Steroids. B: Ch.3: 65-70; Ch7: 167-173
S: Ch. 3.4; Ch 6.1		 LH LP   M* W* Pp PPp NAR PP
4 (C) Th
9/17/15		 Lipids: Fats. Phospholipids. Membranes. Proteins: Amino acids. Stereo-isomers. B: Ch.3: 41-48; Ch.2: 21-22
S: Ch. 3.2		 LH LP   M W Pp PPp Nar PP
5 (C) Tu
9/22/15		 Protein structure. Peptide bonds. Small molecule separation methods. Alpha helix. Beta sheet. B: Ch. 3: 48-54
S: Ch. 3.2 again		 LH LP   M W Pp PPp Nar
PP
6 (C) Th
9/24/15		 3-D structure. Domains.  Quaternary structure. Prosthetic groups.     B: Ch.7:161-162,179
 		 LH LP   M W Pp PPp Nar PP
7 (C) Tu
9/29/15		  Membrane proteins. Protein purification methods. Catalysis. Chemical kinetics. Enzyme kinetics intro. B: Ch.6
S: Ch. 8.3 		LH LP   M W Pp PPp Nar PP
Exam 1 Th
10/1/15

Covers Lecs. 1 to 6.  See Exam 1 page for details. 
Optional review session (Q&A) at morning class time and place.

                  
8 (C) Tu
10/6/15		 Enzyme kinetics cont. Enzyme inhibitors. Feedback inhibition. Free energy and the direction of chemical reactions. ATP hydrolysis. B: Ch. 5
S: 8.1, 8.2, 8.4, 8.5		 LH LP   M W Pp PPp

NarPP
NA :(
9 (C) Th 
10/8/15
 		 Glycolysis as a pathway in intermediary metabolism.  Anaerobiosis. Fermentation. Krebs (TCA) cycle. Electron transport. B: Ch.9: 224-238
S: Ch.9.1 and 9.2		 LH LP   M W Pp PPp NarPP
NA :(

10 (M; C)		 Tu   
10/13/15

Oxidative phosphorylation. ATP synthase. Alternative energy sources. (Dr. C)

DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication (Dr. M) 

Drop date for most schools

 Dr.C: B: Ch.10; S: Ch 9.3 to 9.5; Required: "Carbon" by P. Levi
Optional skim: B:Ch.11/S:Ch.10
Dr. M: B: Ch. 3:54-60 + Box 3A;Ch. 18:505-517
S: Ch. 4.1,13.1 & 13.2  & fig. 15.18 (14.8)

LH-LAC

LH-DM

LP-LAC

LP-DM

 O

M-DM

M-LC

W-DM

W-LC

 Pp PPp NarPP-LC 
Run 
sl.16&23 
movies yourself
11(M) Th
10/15/15		 Wrap up of DNA structure; Details of DNA synthesis. B: Ch. 19:551-567
S: Ch. 13.3 & 13.4		 LH LP O MP3 WMA      
12 (M) Tu
10/20/15		 DNA synthesis cont.; PCR

Intro to Transcription & the central dogma		 B: Box 19A
S: Ch. 13.5  
B: Ch. 21: 645-660 & 674-end.
S: Ch. 14.1 -14.3		 LH LP O MP3 WMA      
Exam#2 Th
10/22/15		 Exam #2. Covers topics of lectures 7 - 11 inclusive. See Exam 2 page (when ready) for details.
Optional review session (Q&A) at morning class time and place.		 4:10 - 5:50 PM or later.                
13 (M) Tu
10/27/15		 Wrap up of transcription; Intro to Translation and the genetic code. B: Ch. 22 to p. 693
S: Ch. 14.5 (14.4 below; 14.6 next term)		 LH LP O MP3 WMA      
14 (M) Th
10/29/15		 Translation & the genetic code, cont.; Mutation (will finish in #15 if necessary) B: Ch. 22: 693-695
S: Ch. 15.1		 LH LP O MP3 WMA      
No class Tu 
11/3/15		 Election Day                  
15 (M) Th
11/5/15		 Regulation of protein synthesis in prokaryotes.  B: Ch. 23 to p. 718.
S: Ch. 16.1 (16.2)		 LH LP O MP3 WMA      
16 (M) Tu
11/10/15		 Bacterial and viral reproduction. B: Ch. 20: 620-624 & Box 18A (p.508-509)
S: Ch. 12.6 & 16.3 (16.1)		 LH LP O MP3 WMA      
17 (M) Th
11/12/15		 Bacterial & Viral reproduction, cont. &

Recombinant DNA technology I. Restriction enzymes & forensics. Blots and probes.

B: Ch. 18: 518-520
& Boxes 18B & 18C
S: Ch. 15.3 (15.2)		 LH LP O MP3 WMA      
18 (M) Tu
11/17/15		 Recombinant DNA tech. II. Molecular cloning;

Discoveries about Eukaryotic gene/genome structure. Introns and exons.

 B: Ch 20: 628-end.  
S. Ch. 18
B: Ch. 21: 669-674.
S: Ch. 14.4 		LH LP O MP3 WMA      
Exam #3 Th
11/19/15		 Exam #3: Covers topics of lectures 12-17. Exam 3 Info Page will be posted with details. 
Optional review session (Q & A) at morning class time and place.

P/D/F deadline

 4:10 - 5:50 PM or later.
 		                
19 (M) Tu
11/24/15		 Wrap up of Recombinant DNA; Then (probably after TK) -- Eukaryotic cell division I: Mitosis and the cell cycle (details of cell cycle and chromosome structure next term); intro to meiosis B: Ch. 19: 549-551 & 571-580.
S: Ch. 11.1-11.3		 LH LP O MP3 WMA      
No class 11/26/15 Thanksgiving                  
20 (M) Tu
12/1/15		 Eukaryotic cell division I -- see readings for Lect. #19
Eukaryotic cell division II & Intro to eukaryotic genetics: Meiosis & its consequences -- sex determination, non- disjunction, life cycles and intro to simple inheritance.		 B: Ch. 20: to p 612.
S: Ch. 11.4-11.5		 LH LP O MP3 WMA      
21(M) Th
12/3/15		 Eukaryotic Genetics I: One gene at a time. Crosses & Genetic diseases. B: Ch. 20: 612-618
S: Ch. 12.1, 12.2, & 12.4 pp. 249-252 (256-259). (skip dihybrid crosses for now)		 LH LP O MP3 WMA      
22 (M) Tu
12/8/15		 Crosses with more than one gene at a time. Intro to Linkage and mapping B: Ch. 20: 618-620
S: Ch. 12.3 & 12.4; Ch. 15.2, 15.4, & 15.5 (15.3-15.6) 		LH LP O MP3 WMA      
23 (M) Th
12/10/15		 Wrap up of linkage; Darwinian evolution, population genetics and molecular evolution  S: Ch. 1.1 (1.1 & & 1.2); Ch. 21 & Ch. 24 LH LP O MP3 WMA      
Review  (M) TBA Optional, date and room TBA                  
FINAL EXAM Tuesday
12/22/15

9:10-12:00;
& 12:10-3 		Exam #4.   EMPHASIZES LECTURES 18 23, but will refer back to entire course.
Important: C2005, section 1 students: This is not the time that was originally posted. We apologize for the change.  Since the exam is earlier, not later, in the day, we assume it will be okay. We hope there will be no problem about tickets to go home.
 Rooms TBA 		                
** Students with class or work conflicts at 4:10 may take the exam at 5:40 (requires permission, including proof of class conflict: CU SSOL printout of schedule with your name or a note from employer). Students with class or work conflicts at 4:10 and/or 5:40 must contact the course assistant Amanda Molina (am4492, 600 Fairchild, 854-5388) at least one week in advance.

++Download codes:

LH, lecture texts in html, best for viewing on a screen                                                                                                     *audio truncated at 45'  :(

LP, lecture texts as pdf, best for printing

M, audio of lecture in mp3 format

W, audio of lecture in WMA format

PP, PowerPoint with narration, if used in lecture

O, outlines for lectures 10-end.
Web lectures and outlines are usually provided by the early morning hours before live lectures 1-9. Materials for lectures 10-23 are usually ready by 9 pm the night before. All of the 2014 lectures are available for those who want to look ahead. (See link at top of page.) There are links to figures in the 9th ed. of Savada embedded in the lectures.  Answered questions posed by students in previous years are also provided: follow the red Q&A links to see a more complete explanation; the green Q&A links expand upon a subject.
Savada and Purves refer to the same basic text: Sadava is the first author from the 8th edition on, Purves was the first author of editions 1-7.
Note: Regarding exams, students are responsible for the material presented in lectures, the Web lectures text, the handouts, and the problems.  The texts should be used to help understand the lectures; you are not responsible for any topics or information that is in the text but not in the live and Web lectures, handouts, or problems. Additional material is sometimes provided in the Web lectures in the form of links to outside sources and links to additional pictures and diagrams; you are only responsible for the information seen on the Web Lectures and the handouts.