rl16.html

Biology UN2005/UN2401 - 2016 Intro Bio Midterm dates will be the following Thursdays: 9/29/16, 10/20/16, & 11/17/16.

Schedule of Lectures, recommended readings, exams, and download links
Students with older editions of the texts can consult older reading lists and find the readings for the same topics.
To study lecture material in advance you may access those from last year which are usually very similar.
See additional notes below.

		++Download codes: LH, lecture notes in html; LP, lecture notes as pdf; O, outline M, mp3 audio of lecture	W, WMA audio of lecture; PP, PowerPoint PPp, Powerpoint as pdf (some loss)	For readings: B = Becker 9^th ed. S = Sadava10^th ed. (refs to previous ed. of text are in paren. if different.)	Lecture notes, recording, etc. -- links added as we go.
Lecture: (P)rice, (M)owsh.	Date	Subject of Lecture		Recommended reading in Becker or Sadava	Downloads
1 (P)	Tu 9/6/16	Introduction. Living things. Cells. Exponential growth.		B: Ch.1;Ch.2:21-36 (18-32); Ch.4:77-81 (75-79) S: Ch 1 + Ch 5.1+5.2	LP	PP	PPp	M	W
2 (P)	Th 9/8/16	Water. Strong and weak chemical bonds. Functional groups. Small vs. large molecules. Bio-polymers. Acids and bases.		B: Ch.3: 48-49 (46-47); 62-67 (60-66) S: Ch.2; Ch 3.1, 3.3	LP	PP	PPp	M	W
3 (P)	Tu 9/13/16	Sugars. Polysaccharides. Lipids: Steroids.		B: Ch.3: 66-71 (65-70); Ch7: 161-168 (167-173) S: Ch. 3.4; Ch 6.1	LP	PP	PPp	M	W
4 (P)	Th 9/15/16	Lipids: Fats. Phospholipids. Membranes. Proteins: Amino acids. Stereo-isomers.		B: Ch.3: 42-50 (41-48); Ch.2: 25 (21-22) S: Ch. 3.2	LP	PP	PPp	M	W
5 (P)	Tu 9/20/16	Protein structure. Peptide bonds. Small molecule separation methods. Alpha helix. Beta sheet.		B: Ch. 3: 50-57 (48-54) S: Ch. 3.2 again	LP	PP	PPp	M	W
6 (P)	Th 9/22/16	3-D structure. Domains. Quaternary structure. Prosthetic groups.		B: Ch.7:157-158 (161-162); 171-173 (179)	LP	PP	PPp	M	W
7 (P)	Tu 9/27/16	Membrane proteins. Protein purification methods. Catalysis. Chemical kinetics. Enzyme kinetics intro.		B: Ch.6 S: Ch. 8.3	LP	PP	PPp	M	W
Exam 1	Th 9/29/16	Covers Lecs. 1 to 6. See Exam 1 page (when ready) for details. Optional review session (Q&A) at morning class time and place.
8 (P)	Tu 10/4/16	Enzyme kinetics cont. Enzyme inhibitors. Feedback inhibition. Free energy and the direction of chemical reactions. ATP hydrolysis.		B: Ch. 5 S: 8.1, 8.2, 8.4, 8.5	LP	PP	PPp	M	W
9 (P)	Th 10/6/16	Glycolysis as a pathway in intermediary metabolism. Anaerobiosis. Fermentation. Krebs (TCA) cycle. Electron transport.		B: Ch.9: 215-231 (224-238) S: Ch.9.1 and 9.2	LP	PP	PPp	M	W
10 (M)	Tu 10/11/16. There will be NO pm lecture on this day. We apologize for any inconvenience. Please try to attend the 10:10 lecture in 417 IAB if possible.	If not yet wrapped up: Oxidative phosphorylation. ATP synthase. Alternative energy sources. (Dr. P) DNA as hereditary material. Nucleic acid structure. Introduction to DNA replication (Dr. M) Drop date for most schools		B: Ch.10; S: Ch 9.3 to 9.5; Required: "Carbon" by P. Levi Optional skim: B:Ch.11/S:Ch.10 B: Ch. 3.2 (Ch. 3, Nucleic Acids) & Ch. 16.1 & 16.2 (Ch. 18, 505-517) S: Ch. 4.1,13.1 & 13.2 & fig. 15.18 (14.8)	LH (DNA) LP (MAP)	LP(DNA) PP (MAP)	O (DNA) PPp (MAP)	M (DNA) M (MAP)	W (DNA) W (MAP)
11(M)	Th 10/13/16	Wrap up of DNA structure; Details of DNA synthesis.		B: Ch. 17.1 (Ch. 19, DNA replication). S: Ch. 13.3 & 13.4	LH	LP	O	M	W
12 (M)	Tu 10/18/16	DNA synthesis cont.; PCR Intro to Transcription & the central dogma		B: Ch. 17 - PCR (Box 19A) S: Ch. 13.5 B: Ch. 18.1, pp. 510, 531. (Ch. 21: 645-660 & 674-end.) Skip euk. details. S: Ch. 14.1 -14.3	LH	LP	O	M	W
Exam#2	Th 10/20/16	Exam #2. Covers topics of lectures 7 - 11 inclusive. See Exam 2 page (when ready) for details. Optional review session (Q&A) at morning class time and place.		4:10 - 6 PM or later.
13 (M)	Tu 10/25/16	Wrap up of transcription; Intro to Translation and the genetic code.		B: Ch. 19.1 & 19.2 (Ch. 22 to p. 693) S: Ch. 14.5 (14.4 below; 14.6 next term)	LH	LP	O	M	W
14 (M)	Th 10/27/16	Translation & the genetic code, cont.; Mutation (will finish in #15 if necessary)		B: Ch. 19.3 (Ch. 22: 693-695) S: Ch. 15.1	LH	LP	O	M	W
15 (M)	Tu 11/1/16	Regulation of protein synthesis in prokaryotes.		B: Ch. 20.1 to p. 576. (Ch. 23 to p. 718.) S: Ch. 16.1 (16.2)	LH	LP	O	M	W
16 (M)	Th 11/3/16	Bacterial and viral reproduction.		B: Ch. 25.5 & fig. 16-3. (Ch. 20: 620-624 & Box 18A) S: Ch. 12.6 & 16.3 (16.1)	LH	LP	O	M-am (short) M-pm (too long)	W-am W-pm
No class	Tu 11/8/16	Election Day
17 (M)	Th 11/10/16	Bacterial & Viral reproduction, cont. & Recombinant DNA technology I. Restriction enzymes & forensics. Blots and probes.		B: Ch. 21.1 & p.638. (Ch. 18: 518-520 & Boxes 18B & 18C) S: Ch. 15.3 (15.2)	LH	LP	O	M	W
18 (M)	Tu 11/15/16	Recombinant DNA tech. II. Molecular cloning; Discoveries about Eukaryotic gene/genome structure. Introns and exons.		B: Ch. 21.4. (Ch 20: 628-end. ) S. Ch. 18 B: Ch. 18.3 pp. 526- 530. (Ch. 21: 669-674.) Introns & splicing. S: Ch. 14.4	LH	LP	O	M	W
Exam #3	Th 11/17/16	Exam #3: Covers topics of live lectures 12-17. Exam 3 Info Page is posted with details. Optional review session (Q&A) at morning class time and place. P/D/F & W deadline		4:10 - 6 PM or later.
19 (M)	Tu 11/22/16	Note: We are about 1 lecture behind. We will finish Recombinant DNA in #19. Next time in #20: Eukaryotic cell division I: Mitosis and the cell cycle (details of cell cycle and chromosome structure next term); intro to meiosis		B: Ch. 24.1 & 24.2. (Ch. 19: 549-551 & 571-580.) S: Ch. 11.1-11.3	LH	LP	O	M	W
*No class -- Enjoy the holiday!!*	11/24/16	Thanksgiving
20 (M)	Tu 11/29/16	Today: Wrap up of Recombinant DNA, & Eukaryotic cell div. I. (See readings above.) Next Time: Eukaryotic cell division II & Intro to eukaryotic genetics: Meiosis & its consequences -- sex determination, non- disjunction, life cycles and intro to simple inheritance.		B: Ch. 25.1 & 25.2 (Ch. 20: to p 612.) S: Ch. 11.4-11.5	LH	LP	O	M	W
21(M)	Th 12/1/16	Eukaryotic Genetics I: One gene at a time. Crosses & Genetic diseases.		B: Ch. 25.3 (Ch. 20: 612-618) S: Ch. 12.1, 12.2, & 12.4 pp. 249-252 (256-259). (skip dihybrid crosses for now)	LH	LP	O	M	W
22 (M)	Tu 12/6/16	Crosses with more than one gene at a time. Intro to Linkage and mapping		B: Ch. 25.4. (Ch. 20: 618-620) S: Ch. 12.3 & 12.4; Ch. 15.2, 15.4, & 15.5 (15.3-15.6)	LH	LP	O	M	W
23 (M)	Th 12/8/16	Wrap up of linkage; Darwinian evolution, population genetics and molecular evolution		S: Ch. 1.1 (1.1 & & 1.2); Ch. 21 & Ch. 24	LH	LP	O	M	W
Review (M) -- Q & A	Thurs, 12/15 -- 2 dif. times	Review #1: 11-1, Broadway Sky Lounge (14th floor). Review #2 -- 6:30 to 8 pm; room TBA
FINAL EXAM	Tuesday 12/20/16 Most. 4:10-7; a later session for those with conflicts will be set up, prob. 7-10.	Exam #4. EMPHASIZES LECTURES 18-23, but will refer back to entire course. Important: C2005, section 1 students: This is not the usual time for a class that meets Tu-Th at 10:10. Please take this into account when buying tickets to go home.		Rooms TBA
** 110 minutes (4:10 to 6) will be scheduled for exams, assuming availability of rooms. Students with class or work conflicts at 4:10 may take the exam later -- time TBA (requires permission, including proof of class conflict: CU SSOL printout of schedule with your name or a note from employer). Students with class or work conflicts at both times must contact the course assistant Amanda Molina (am4492, 600 Fairchild, 854-5388) at least one week in advance.
++Download codes: LH, lecture texts in html, best for viewing on a screen LP, lecture texts or PP in pdf, best for printing M, audio of lecture in mp3 format W, audio of lecture in WMA format PP, PowerPoint, if used in lecture O, outlines for lectures 10-end.
Web lectures and outlines are usually provided by the early morning hours before live lectures 1-9. Materials for lectures 10-23 are usually ready by 9 pm the night before. All of the 2015 lectures are available for those who want to look ahead. (See link at top of page.) There are links to figures in the 9th ed. of Savada embedded in the lectures. Answered questions posed by students in previous years are also provided: follow the red Q&A links to see a more complete explanation; the green Q&A links expand upon a subject.
Savada and Purves refer to the same basic text: Sadava is the first author from the 8th edition on, Purves was the first author of editions 1-7.
Note: Regarding exams, students are responsible for the material presented in lectures, the Web lectures text, the handouts, and the problems. The texts should be used only to help understand the lectures; you are not responsible for any topics or information that is in the text but not in the live and Web lectures, handouts, or problems. Additional material is sometimes provided in the Web lectures in the form of links to outside sources and links to additional pictures and diagrams; you are only responsible for the information seen on the Web Lectures and the handouts.