Tetrad analysis and mapping in fungi – mapping with a centrosome and with identified products of meiosis

Observations to be explained by any model of recombination

1. Gene Conversion

2. Polarity - gradient of gene conversion events

3. Half of all conversion events are associated with recombination

4. Co-conversion

Models for recombination and gene conversion

1. Holliday model

2. Double stranded break repair model