1. Making mutations

    1. Types of changes

    2. How they occur

    3. Induced

      1. Replace a base

      2. Alter a base

      3. Link bases

      4. Breaks

      5. Insertion

    4. DNA synthesis and repair can lead to mutation

  2. Mutators

    1. Mutations in correcting systems will cause increase in mutation rate

    2. Transposons

  3. Ames test

  4. Reversion tests to see what the mutagen is

    1. Point mutations

    2. Frame shifts

    3. Deletions

  5. Transposons