General Course Information:

EEEB W2001.001 Environmental and Evolutionary Biology I: Molecules to Cells

TR     01:10P-02:25P

614 SCHERMERHORN

 

Instructor Information:

 

Robert E., Pollack

E-mail:  [email protected]

Intended audience:

 

First- and second-year students who have not yet taken general chemistry, and premedical students with any major. While all students from all undergraduate schools of the University who are interested in the subjects covered are welcome as well, this course is designed to meet the particular requirements of the following  majors in the College:

 

 

            Biology, if followed by BIOL 2006. General Chemistry should be taken concurrently.

 

            Environmental Biology, if accompanied by EEEB 2002.

 

This major is sponsored jointly by the Departments of Biology and EEEB. 

 

Premedical students in any year may take this course and BIOL 2006 to satisfy the pre-med requirement of a year of introductory biology. See the Pre-professional office of your school for details.

 

Required Textbook:

 

"Biological Science," 2nd Edition, by Scott Freeman, published by Prentice Hall in 2005, is required for this course.  The 2002 First edition is not as good, and all references in the course will be to the second edition.

 

"Signs of Life," by Robert Pollack, published in paperback by Houghton Mifflin, is strongly recommended.

 

Chapters of each book are indicated in the syllabus for each class. Chapters are identified by the author's last name's initial and chapter number (e.g. Chapter 1 in Freeman will appear on the syllabus as "F1" and Chapter 1 in Pollack will appear as "P1").

 

Recommended books:

Other books on reserve in the Biology library, 6th floor Fairchild, include

 

            L. Margulis, "Early Life;"

            R. Dawkins, “Climbing Mount Improbable;”

            R. Pollack, "The Missing Moment."

            M. Rose, “Evolution and Ecology of the Environment”

 

Exams and grades:

Classes, recitations and exams will be organized so as to accommodate religious observances wherever possible. 

 

Exams and recitations will be based on class lectures rather than textbook content, so regular attendance in class and recitation is strongly encouraged. The grade for the course is based on class rank on two midterm exams and a final exam along with participation in recitation and lecture.  From the sum of these three, a final grade will be assigned according to cutoffs to be determined by the instructors after the final exam.

 

The instructors are always available by email appointment to discuss any aspect of this course during the semester.  

 

Further Information:

Answers to students' questions and other useful items will be posted on Courseworks. 

 

In the fall semester the following secular and religious observances (taken from the nyc.gov website) will impact on the syllabus.

 

Rosh Hashanah: First/Second Day

October 4-5, Tues-Wed

Yom Kippur

October 13, Thurs

Succoth: First/Second Day

October 18-19, Tues-Wed

Shemini Atzereth

October 25, Tues

Idul-Fitr: First Day

November 3, Thurs

Election Day

November 8, Tues

Thanksgiving Day

November 24, Thurs

 

 

 

 Syllabus                                                                                                                            Fall 2005

 

Environmental and Evolutionary Biology I: Molecules to Cells

 

Class         Date             Topic                                                                             Readings

 

Modern cell biology from an evolutionary point of view.

   1             9/6    T        I: Introduction                                                                   F1

                  9/7    W             Recitation

   2             9/8    R        II: Natural selection                                                           F1

                  NOTES:  lecture 1, lecture 2

 

The origin of molecules.

   

   3             9/13  T        I: Atoms, molecules, bonds, water                                   F2

                  9/14  W             Recitation

   4             9/15  R        II: Biological molecules; lipids and polysaccharides        F5, 6

   5             9/20  T        III: Proteins and nucleic acids                                           F3, 4

                  9/21  W       Recitation                                                                           

                  NOTES:  lecture 3, lecture 4, lecture 5

                 

The origin of cells.

   

   6             9/22  R        I: Prokaryotes, endosymbiosis and eukaryotes                F7, 28

  7              9/27  T        II: The membranes of cells today, trans-membrane        F8

                                             proteins, cell-cell interaction

                  9-28   W             Recitation

                  NOTES:  lecture 6, lecture 7

 

The origin of energy transfer systems.

   

   8             9/29 T          I: Introduction to useful energy                                        F2

Exam I      10/3 M         ** Exam I: lectures 1-7 **

   9             10/6 R         II: Energy and the history of cells                                     F2

   10           10/11 T        III: Energy in bonds vs. energy in movement                  F6

                  10/12           W                                                                                        No Recitation

   11           10/17 M      IV: Glycolysis and fermentation                                       F9

                  10/19           W                                                                                        Recitation

   12           10/20 R       V: Chemiosmosis and photosynthesis                              F10

   13           10/24 M      VI: Chemiosmosis and oxidative phosphorylation;         F9

                                             summary of evolution of energy transfer

                  NOTES:  lecture 8, lecture 9, lecture 10, lecture 11, lecture 12, lecture 13

 

The origin of information transfer systems.

   

   14           10/27           R    I. Using energy to conserve genetic information       F14; P1,2                                                   

   15           10/31 M      II: Prokaryote versus eukaryote inheritance                    F15; P1, 2

    16          11/1  T        III: Mitosis, meiosis, cell cycle                                           F11,12; P1, 2

                  11/2  W       Recitation

   17           11/10           R                                                                                         IV: Linkage maps, human phenotypes         F13; P5

                  NOTES:  lecture 14, lecture 15, lecture 16, lecture 17

 

The molecules of information transfer.

   

   18           11/14 M      I: DNA: the genetic molecule                                            F14,20;  P2, 3

   19           11/15           T                                                                                         II: DNA replication, RNA transcription       F15, 16;  P3, 4

                  11/16           W                                                                                        Recitation – Exam Review

Exam II     11/17 R        ** Exam II: lectures 8-17 **

  

   20           11/22           T                                                                                         III: RNA translation    F16; P3, 4, 5

   21           11/29 T        IV: Gene regulation                                                           F17, 18; P3, 4, 5

                  NOTES:  lecture 18, lecture 19, lecture 20, lecture 21

 

Evolution from a molecular point of view

   22           12/1  R        I: Origins of genetic variation: mutation,                         F23,24;  P5, 6

                                          non-reciprocal recombination, gene families.

   23           12/6  T        II: Microevolution by loss of HW equilibrium due           F24

                                            to selection

                  12/7  W             Recitation

   24           12/8  R        III: Macroevolution from microevolution: speciation      F25

                  NOTES:  lecture 22, lecture 23, lecture 24

 

   ***          TBD             Reading Period / Review Session