Endocrine control of lactation
Wednesday, September 8: Homeostasis; Temperature regulation
- Claude Bernard
- Homeostasis
- Temperature regulation
Required reading:
Jared Diamond, "Pearl Harbor and the Emperor's
Physiologists", Natural
History, Dec 1991, pp. 2-8
Recommended reading:
Sherwood: 2-12; 607-617; 408-410
Claude Bernard
biography
Painting of Bernard
performing animal experiments
Monday, September 13: Communication between cells; Berthold
- Communication between cells
- Berthold
Recommended reading:
Sherwood: 621-635
Discovery of prostaglandins:
Research and biographies of the scientists who won the Nobel Prize for their work in this
field.
You should already know:
Cell structure, how stuff gets across membranes,
signal transduction. Purves: 71-116 or Sherwood: 17-27,
35-70
Wednesday, September 15: Measuring hormones
- Bioassay
- Radioimmunoassay
Recommended reading:
"Hormone Measurement: Radioimmunoassay" Berne and Levy, Physiology, 3rd edition, Mosby-Year Book, 1993, pages 828-830. (A brief description of this technique)
1977 Nobel prize Describes development of RIA and isolation of hypothalamic hormones, and autobiographies of the laureates, Rosalyn Yalow, Roger Guillemin, Andrew Schally.
Wednesday, September 22: Measuring hormones; Lactation
- ELISA
- Hypothalamus and pituitary gland
- Endocrine control of lactation
Recommended reading:
Sherwood, 637-644; 740-742; 744-746
Introduction to ELISA activity. Animation of another type of ELISA. another elisaanotherYou should already know:
Basic structure of and relationship between hypothalamus and pituitary gland. See pages in Sherwood, above, or Dr. Mowshowitz' notes from 2006/2402: last part of Lecture 13 and first part of Lecture 14