Lecture 13, Monday, October 20:    Stress and Disease

Goals:

 

Lecture:

Osteoporosis
Design of research on stress and disease
Organization of nervous system

Slides

Reading:

Sherwood: 
None

Optional reading:
Osteoporosis research at MGH - describes the use of PTH to treat ostoporosis

Medical reference:
Stressed out from so much schoolwork Advice from Go Ask Alice

Test yourself:

Nuts and Bolts
Problem solving

 

     Lecture 14, Wednesday, October 22:    Stress and Disease

Goals:

 

Lecture:

Communicating about stress

  • via the nervous system
  • via the endocrine system
    • adrenal medulla
    • adrenal cortex

Mini-exam # 3

Slides

Reading:

Sherwood: 
5th ed: 707-717, 527-529, 237-245
4th ed: 675-679, 497-499, 222-229

Recent research:
Weight loss decreases ACE enzyme

Test yourself:

Nuts and Bolts
Problem solving

 

     Lecture 15, Monday, October 27:    Stress and Disease

Goals:

 

Lecture:

Short- and long-term response to stress
Non-specific immunity
Inflammation

Slides

Animations:

Neutrophil exits capillary

Reading:

Sherwood: 
5th ed: 413-424; 451-452 
4th ed: 390-400; 427-429 

Recent research:
"Taming stress", Robert Sapolsky, Scientific American, Sept 2003
"The heavy cost of chronic stress", Erica Goode, NY Times, Dec 17, 2002

Other reading:
Links from PBS

Test yourself:

Nuts and Bolts
Problem solving

 

     Lecture 16, Wednesday, October 29:    Stress and Disease

Goals:

 

Lecture:

Inflammation
Specific immune response 

Slides

Animations:

The bloody characters of specific immunity

Reading:

Sherwood: 
5th ed: 424-445
4th ed: 402-421

Other reading:
Inflammation
Overview of inflammation

Test yourself:

Nuts and Bolts
Problem solving
Problem Set # 6