Post Doctorate/Instructor- The Albert Einstein College of Medicine, Sept. 2000-2004, NIH Cardiovascular fellowship /American Heart Association Scientific Development Fellowship. Aberrant heart development and maintenance are major causes of miscarriages and heart failure. I have created Zebrafish lines using GATA-4 and GATA-6 regulatory regions to reveal in real time the role of these GATA factors in heart development and disease.

EDUCATION

Phd., Weizmann Institute of Science, Israel, July 2000, Transcriptional regulationof the microtubule associated protein, tau and its deregulation in Alzheimer's disease. Outstanding student award.
Advisor: Dr. Irith Ginzburg

M.S. Tel Aviv University, Israel, March 1991, Intermodal compensation in the neonatally enucleated Syrian hamster. Honors

B.A. Penn State University, May 1988. Honors

 Representative Recent Publications

• Vlahos, M., Lazarovici, A. and Heicklen-Klein, A. JN083805 Eruca vesicaria subsp. sativa glyceraldehyde-3-phosphate dehydrogenase (GAPC1) gene, partial cds. 2011
• Barnett, A., Huang, A., Lazarovici, A., Constant, C., Nsibirwa, N. and Heicklen-Klein, A. JN083806 Salvia officinalis glyceraldehyde-3-phosphate dehydrogenase (GAPC2) gene, partial cds. 2011
•  Amaniera, F., Samant, R. and Heicklen-Klein, A. JN086968 Daucus carota glyceraldehyde-3-phosphate dehydrogenase (GAPC1) gene, partial cds. 2011
•  Vhalos, M., Garg, K., Leiner, A., Leonardo, T. and Heicklen-Klein, A. JN086969 Daucus carota glyceraldehyde-3-phosphate dehydrogenase (GAPC2) gene, partial cds. 2011
• Heicklen A. 2011 Summer Undergraduate Research Experience in Stem Cell Science NYSTEM Science Accelerating Therapies Conference abstract p4
• Kachniarz, B., Levites, H., Lefkowitz, A. and Heicklen-Klein, A. HM228871 Spinacia oleracea glyceraldehyde-3-phosphate dehydrogenase (GAPC) gene, partial cds. 2010
• Kachniarz, B., Levites, H., White, P. and Heicklen-Klein, A. HM228872 Solanum lycopersicum glyceraldehyde-3-phosphate dehydrogenase (GAPC) gene, partial cds. 2010
• Heicklen-Klein A., McReynolds L.J. and Evans T. (2005) Using the zebrafish model to study GATA transcription factors, Semin. Cell Dev. Biol. 16: 95-106
• Heicklen-Klein A. and Evans T. (2004) T-Box binding sites are required for activity of a cardiac GATA-4 enhancer. Dev. Biol. 267: 490-504
• Izraeli R., Koay G., Lamish M., Heicklen-Klein A., Heffner H. E., Heffner R. S. and Wollberg Z. (02)Cross-modal neuroplasticity in blind hamsters: structure, electrophysiology, and behavior. Eur. J. Neurosci. 15:693-712.
• Heicklen-Klein A. and Ginzburg I. (2000) Tau promoter confers neuronal specificity and binds Sp1 and AP-2. J. Neurochem. 75(4): 1408-1418.
• Heicklen-Klein A., Aronov S. and Ginzburg I. (2000) Tau promoter activity in neuronally differentiated P19 cells. Mol. Brain Res. 874(1): 1-9.
• Sadot E., Heicklen-Klein A. Barg J., Lazarovici P. and Ginzburg I. (1996) Identification of a tau promoter region mediating tissue-specific-regulated expression in PC12 cells. J. Mol. Biol. 256: 805-812.
• Gur S., Ron S., and Heicklen-Klein A. (1994) Objective evaluation of visual fatigue in VDU workers. Occup. Med. 44: 201-204.
• Gur S., Ron S., and Heicklen-Klein A. (1992) The need for visual impairment evaluation in VDU workers. Arch. Scienze Lav. 8: 125-129.