Biological Sciences Columbia University
Ph.D. Program Faculty
Research Highlights
Postdoctoral Research
Ph.D. Program Faculty

The Department of Biological Sciences has increased the opportunities for graduate student thesis research by including laboratories in various departments at Columbia's College of Physicians and Surgeons (Medical School). This expansion more than doubles the number of faculty sponsors participating in the Department's Ph.D. Program. In the list below, most training faculty are grouped according to one primary field of research, but many could be placed in several such categories. Affiliated laboratories at the College of Physicians and Surgeons on 168th St. & Broadway are indicated with an asterisk (*).

Cell and Molecular BiologyBack to Top Back To Top
Baer, Richard *
Pathology and Cell Biology
Tumor suppression and genome instability in breast cancer
Bulinski, Chloë
Biological Sciences
Dynamics and functions of microtubules during myogenic differentiation and cell cycle progression
Chasin, Lawrence
Biological Sciences
Pre-mRNA splicing in cultured mammalian cells
Dalla-Favera, Riccardo *
Pathology and Cell Biology
Molecular genetics of cancer; molecular pathogenesis of lymphoma and leukemia
Dietrich, Lars
Biological Sciences
Bacterial models for biological shape and pattern formation
Dworkin, Jonathan *
Microbiology & Immunology
Bacterial signaling and interactions with the host
Gautier, Jean *
Genetics & Development | Institute for Cancer Genetics
DNA replication, DNA repair and the DNA damage response in the maintenance of genomic integrity
Goff, Stephen *
Retroviral replication; tyrosine kinase oncogenes
Gu, Wei *
Pathology and Cell Biology
Protein modifications in tumor suppression and aging
Jia, Songtao
Biological Sciences
Epigenetic regulation of the genome
Manley, James
Biological Sciences
Regulation of mRNA synthesis in animal cells
Miller, Elizabeth
Biological Sciences
Vesicle architecture and protein quality control in the secretory pathway
Prives, Carol
Biological Sciences
Structure & function of the p53 tumor suppressor protein
Prywes, Ron
Biological Sciences
Growth factor regulation of gene expression
Rothstein, Rodney *
Genetics & Development
Yeast genetics; mechanisms of genetic recombination; control of genome stability; functional genomics.
Schindler, Chris *
Microbiology | Medicine
JAK-STAT signaling and immune response
Sheetz, Michael
Biological Sciences
Cell motility, motor molecules, integrin-cytoskeleton interactions
Stockwell, Brent
Biological Sciences
Diagramming disease networks with chemical and biological tools
Symington, Lorraine *
Yeast recombination studies in Saccharomyces cerevisiae
Tzagoloff, Alexander
Biological Sciences
Energy coupling mechanisms
Vallee, Richard *
Pathology & Cell Biology
Motor proteins in axonal transport, brain developmental disease, and synaptic function
Developmental BiologyBack to Top Back To Top
Chalfie, Martin
Biological Sciences
Developmental genetics of identified nerve cells in C. elegans
Greenwald, Iva *
Biochemistry & Molecular Biophysics | Genetics & Development
Lin-12/Notch signaling and cell fate specification
Hazelrigg, Tulle
Biological Sciences
Germ Cell Development in Drosophila
Jessell, Thomas *
Biochemistry & Molecular Biophysics | Neuroscience
Molecular mechanisms of neural differentiation
Johnston, Laura *
Genetics & Development
Control of growth and cell division during development
Kalderon, Daniel
Biological Sciences
Signal Transduction in Drosophila development
Mann, Richard *
Biochemistry & Molecular Biophysics
Transcriptional control
Struhl, Gary *
Genetics & Development
Developmental genetics in Drosophila
NeurobiologyBack to Top Back To Top
Axel, Richard *
Biochemistry & Molecular Biophysics | Pathology & Cell Biology
Central and peripheral organization of the olfactory system
Fernández, Julio
Biological Sciences
Single molecule mechanics and engineering
Firestein, Stuart
Biological Sciences
Cellular mechanisms of signal transduction and olfaction
Greene, Lloyd *
Pathology & Cell Biology
Mechanisms of neuronal differentiation and degeneration and their regulation by external growth factors
Grueber, Wesley *
Physiology & Cellular Biophysics | Neuroscience
Molecular basis of nervous system development and function in Drosophila
Hen, René *
Contribution of specific serotonin receptors as well as hippocampal neurogenesis to pathological states such as depression and anxiety
Henderson, Christopher *
Rehabilitation and Regenerative Medicine
Motor neuron biology and disease: developmental mechanisms and therapeutic targets for ALS and SMA
    Hobert, Oliver *
Biochemistry & Molecular Biophysics
Nervous system development and function  
Jessell, Thomas *
Biochemistry & Molecular Biophysics | Neuroscience
Molecular mechanisms of neural differentiation
Kandel, Eric *
Neuroscience | Physiology & Cellular Biophysics | Psychiatry | Biochemistry & Molecular Biophysics
Cell and molecular mechanisms of associative and nonassociative learning
Kelley, Darcy
Biological Sciences
Neurobiology of vocal communication; sexual differentiation
Paninski, Liam *
The statistical analysis of neural and imaging data
Siegelbaum, Steven *
Molecular studies of ion channel structure and function; synaptic transmission and plasticity in the mammalian brain
Yang, Jian
Biological Sciences
structure, function, regulation and cell biology of ion channels.
Yuste, Rafael
Biological Sciences
Development and function of the cortical microcircuitry
Zuker, Charles *
Biochemistry & Molecular Biophysics | Neuroscience
Signal processing, information transfer, and coding mechanisms in sensory systems
Structural Biology and Molecular BiophysicsBack to Top Back To Top
Cornish, Virginia *
Development of in vivo selection strategies for evolving proteins with novel catalytic properties
Fernández, Julio
Biological Sciences
Single molecule mechanics and engineering
Frank, Joachim
Biological Sciences | Structural Biology and Molecular Biophysics
Cryo-electron microscopy and three-dimensional reconstruction for the study of the mechanism of protein biosynthesis
Gonzalez Jr., Ruben *
Mechanistic studies of protein synthesis by the ribosome using single-molecule fluorescence microscopy and other biophysical and biochemical approaches
Greene*, Eric *
Biochemistry & Molecular Biophysics
Molecular mechanisms of DNA recombination and repair; single molecule fluorescence microscopy and other biochemical approaches.
Hendrickson, Wayne *
Biochemistry & Molecular Biophysics
Macromolecular structure; X-ray crystallography
Hunt, John
Biological Sciences
Structural biology of transmembrane transport
McDermott, Ann *
Chemistry | Biological Sciences | Chemical Engineering
Solid-state NMR studies of enzyme mechanism and membrane protein structure
Palmer, Arthur *
Biochemistry & Molecular Biophysics
Biomolecular dynamics, structure, and function; NMR spectroscopy
Sahin, Ozgur
Biological Sciences
Imaging and Modeling Biology at Physical Extremes
Tong, Liang
Biological Sciences
Structural biology of proteins involved in human diseases (obesity, diabetes, cancer); Structural biology of proteins involved in pre-mRNA 3'-end processing.
Yang, Jian
Biological Sciences
structure, function, regulation and cell biology of ion channels.
Systems and Computational BiologyBack to Top Back To Top
Anastassiou, Dimitris *
Electrical Engineering | Systems Biology
Data mining of large biological datasets - cancer research
Bussemaker, Harmen
Biological Sciences
Data-driven predictive modeling of transcriptional and post-transcriptional networks based on biophysical principles
Califano, Andrea *
Biomedical Informatics
Study of gene regulatory and signaling networks in mammalian cellular contexts using computational methods.
Pe'er, Dana
Biological Sciences
The function and organization of molecular networks
Pe'er, Itsik *
Computer Science
Novel computational methods in human genetics
Pickrell, Joseph
Biological Sciences
Computational and statistical approaches to human genomics
Przeworski, Molly
Biological Sciences
Population genetics, evolutionary genetics, meiotic recombination
Sella, Guy
Biological Sciences
Evolutionary genetics of adaptation, disease risk and other quantitative traits