FACULTY RESEARCH Ph.D. PROGRAM M.A. BIOTECHNOLOGY UNDERGRADUATE COURSES RESEARCH Ph.D. Program Faculty Research Highlights Postdoctoral Research Ph.D. Program Faculty The Department of Biological Sciences has increased the opportunities for graduate student thesis research by including laboratories in various departments at Columbia's College of Physicians and Surgeons (Medical School). This expansion more than doubles the number of faculty sponsors participating in the Department's Ph.D. Program. In the list below, most training faculty are grouped according to one primary field of research, but many could be placed in several such categories. Affiliated laboratories at the College of Physicians and Surgeons on 168th St. & Broadway are indicated with an asterisk (*). Name Interests Cell and Molecular Biology Back to Top Bulinski, Chloë Biological Sciences Dynamics and functions of microtubules during myogenic differentiation and cell cycle progression Chasin, Lawrence Biological Sciences Pre-mRNA splicing in cultured mammalian cells Gautier, Jean * Genetics & Development | Institute for Cancer Genetics Cell cycle and cell death during early development Jia, Songtao Biological Sciences Epigenetic regulation of the genome Manley, James Biological Sciences Regulation of mRNA synthesis in animal cells Miller, Elizabeth Biological Sciences Protein folding, assembly and the regulation of intracellular protein transport. Prives, Carol Biological Sciences Structure & function of the p53 tumor suppressor protein Prywes, Ron Biological Sciences Growth factor regulation of gene expression Rothstein, Rodney * Genetics & Development Yeast genetics; mechanisms of genetic recombination; control of genome stability; functional genomics. Schindler, Chris * Microbiology | Medicine JAK-STAT signaling and immune response Sheetz, Michael Biological Sciences Cell motility, motor molecules, integrin-cytoskeleton interactions Stockwell, Brent Biological Sciences Diagramming disease networks with chemical and biological tools Symington, Lorraine * Microbiology Yeast recombination studies in Saccharomyces cerevisiae Tzagoloff, Alexander Biological Sciences Energy coupling mechanisms Vallee, Richard * Pathology & Cell Biology Motor proteins in axonal transport, brain developmental disease, and synaptic function Developmental Biology Back to Top Chalfie, Martin Biological Sciences Developmental genetics of identified nerve cells in C. elegans Greenwald, Iva * Biochemistry & Molecular Biophysics Lin-12/Notch signaling and cell fate specification Hazelrigg, Tulle Biological Sciences mRNA localization in Drosophila oocytes Hobert, Oliver * Biochemistry & Molecular Biophysics Nervous system development and function Jessell, Thomas * Biochemistry & Molecular Biophysics | Center for Neurobiology & Behavior Molecular mechanisms of neural differentiation Johnston, Laura * Genetics & Development Control of growth and cell division during development Kalderon, Daniel Biological Sciences Signal Transduction in Drosophila development Mann, Richard * Biochemistry & Molecular Biophysics Transcriptional control Papaioannou, Virginia * Genetics & Development Genetic control of mammalian development in the peri-implantation period Struhl, Gary * Genetics & Development Developmental genetics in Drosophila Neurobiology Back to Top Axel, Richard * Biochemistry & Molecular Biophysics | Pathology & Cell Biology Central and peripheral organization of the olfactory system Fernández, Julio Biological Sciences Single molecule mechanics and engineering Firestein, Stuart Biological Sciences Cellular mechanisms of signal transduction and olfaction Greene, Lloyd * Pathology & Cell Biology Mechanisms of neuronal differentiation and degeneration and their regulation by external growth factors Hen, René * Pharmacology Serotonin receptors and behavior Jessell, Thomas * Biochemistry & Molecular Biophysics | Center for Neurobiology & Behavior Molecular mechanisms of neural differentiation Kandel, Eric * Physiology & Cellular Biophysics | Psychiatry | Biochemistry & Molecular Biophysics Cell and molecular mechanisms of associative and nonassociative learning Kelley, Darcy Biological Sciences Neurobiology of vocal communication; sexual differentiation Siegelbaum, Steven * Pharmacology Molecular studies of ion channel structure and function; synaptic transmission and plasticity in the mammalian brain Yang, Jian Biological Sciences Structure, function and regulation of ion channels Yuste, Rafael Biological Sciences Development and function of the cortical microcircuitry Structural Biology and Molecular Biophysics Back to Top Cornish, Virginia * Chemistry Development of in vivo selection strategies for evolving proteins with novel catalytic properties Fernández, Julio Biological Sciences Single molecule mechanics and engineering Frank, Joachim Biological Sciences | Structural Biology and Molecular Biophysics Cryo-electron microscopy and three-dimensional reconstruction for the study of the mechanism of protein biosynthesis Greene*, Eric * Biochemistry & Molecular Biophysics Molecular mechanisms of DNA recombination and repair; single molecule fluorescence microscopy and other biochemical approaches. Hendrickson, Wayne * Biochemistry & Molecular Biophysics Macromolecular structure; X-ray crystallography Hunt, John Biological Sciences Structural biology of transmembrane transport Karlin, Arthur * Biochemistry & Molecular Biophysics | Physiology & Cellular Biophysics | Center for Molecular Recognition Molecular mechanisms of receptor function. McDermott, Ann Chemistry | Biological Sciences | Chemical Engineering Solid-state NMR studies of enzyme mechanism and membrane protein structure Palmer, Arthur * Biochemistry & Molecular Biophysics Biomolecular dynamics, structure, and function; NMR spectroscopy Tong, Liang Biological Sciences Structural biology of proteins involved in human diseases (obesity, diabetes, cancer); Structural biology of proteins involved in pre-mRNA 3'-end processing. Yang, Jian Biological Sciences Structure, function and regulation of ion channels Systems and Computational Biology Back to Top Bussemaker, Harmen Biological Sciences Data-driven modeling of transcriptional and post-transcriptional networks based on biophysical principles Califano, Andrea * Biomedical Informatics Study of gene regulatory and signaling networks in mammalian cellular contexts using computational methods. Pe'er, Dana Biological Sciences The function and organization of molecular networks HOME DIRECTORIES NEWS & EVENTS RESOURCES EMPLOYMENT CONTACT US