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Quantitative Proteomics Center
Department of Biological Sciences
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Some recent publications:
Elizabeth Oswald, Lewis M.Brown, J. Chloe Bulinski, Clark T. Hung. 2011. Label-Free Protein Profiling of Adipose-Derived Human Stem Cells under Hyperosmotic Treatment. J. Proteome Res. 10: 3050-3059. PMID: 21604804
Dustin L. Higashi, Nicolas Biais, Nathan J. Weyand, Al Agellon, Jennifer L. Sisko, Lewis M. Brown, Magdalene So (2011) N. elongata Produces Type IV Pili That Mediate Interspecies Gene Transfer with N. gonorrhoeae. PLoS ONE 6(6): e21373.doi:10.1371/journal.pone.0021373
Masha V. Poyurovsky, Chen Katz, Oleg Laptenko, Rachel Beckerman, Maria Lokshin, Jinwoo Ahn, In-Ja L.Byeon, Ronen Gabizon, Melissa Mattia, Andrew Zupnick, Lewis M. Brown, Assaf Friedler, Carol Prives 2010. The C terminus of p53 binds the N-terminal domain of MDM2. Nat Struct Mol Biol. 17: 982-989
Christopher J. Cardinale, Robert S. Washburn, Vasisht R. Tadigotla, Lewis M. Brown, Max E. Gottesman, and Evgeny Nudler (2008) Termination Factor Rho and Its Cofactors NusA and NusG Silence Foreign DNA in E. coli. Science 320 (5878): 935 - 938.
Jost Klawitter, Christopher J. Rivard, Lewis M. Brown, Juan M. Capasso, Nestor E. Almeida, Arvid B. Maunsbach, Kaarina Pihakaski-Maunsbach, Tomas Berl, Dieter Leibfritz, Uwe Christians, Laurence Chan (2008) A Metabonomic and Proteomic Analysis of Changes in IMCD3 Cells Chronically Adapted to Hypertonicity. Nephron Physiol 109:1-10.
Augusto Uc-Mass, Arkady Khodursky, Lewis M. Brown, and Max E. Gottesman (2008) Overexpression of phage HK022 Nun protein is toxic for Escherichia coli. J. Mol. Biol. 380 (5): 812-819
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Christopher J. Rivard, Lewis M. Brown, Nestor E. Almeida, Arvid B. Maunsbach, Kaarina Pihakaski-Maunsbach, Ana Andres-Hernando, Juan M. Capasso, and Tomas Berl (2007) Expression of the calcium binding protein S100A4 is markedly up-regulated by osmotic stress and is involved in the renal osmoadaptive response. J. Biol. Chem. 282: 6644-6652.
Lewis M. Brown, Steve M. Helmke, Stephen W. Hunsucker, Romana T. Netea-Maier, Simon A. Chiang, David E. Heinz, Kenneth R. Shroyer, Mark W. Duncan, and Bryan R. Haugen (2006) Quantitative and qualitative differences in protein expression between papillary thyroid carcinoma and normal thyroid tissue. Molecular Carcinogensis 45: 613-626.
Charles A. Blake, Lewis M. Brown, Mark W. Duncan, Stephen W. Hunsucker, and Steve M. Helmke (2005) Estrogen Regulation of the Rat Anterior Pituitary Gland Proteome. Experimental Biology and Medicine. 230: 800-807.