always been fascinated by scientific theories and learning how things work, but
my interest in experimental research was piqued during a summer internship at
the University of Montreal. I studied the acetylation and de-acetylation on a
lysine residue in histone H3, and its role on DNA repair mechanisms. This was
an eye-opening experience. I learned how science develops new knowledge, and
how it creates clear pictures of microscopic phenomena, occasionally from
unsuspected indirect methods.
graduating from the University of Quebec at Montreal with a BSc in
biochemistry, I moved to Florida, one block away from the Atlantic Ocean, to
work at the Mayo Clinic as a laboratory technician. I studied the interactions
of proteases with their small protein inhibitors using x-ray crystallography,
biochemical assays and site-directed mutagenesis. I discovered why a
metastasis-causing protease, mesotrypsin, is resistant to inhibition by potent
trypsin inhibitors. My results will hopefully open up an avenue to developing
therapeutic inhibitors of mesotrypsin that could slow down cancer progression
two experiences, I became very interested not only in theories and abstract
ideas, but also in experimentation, observation, and in the interpretation of
Columbia, I would like to study the workings of biologically relevant molecules
at the atomic scale and to gain a better understanding of how biological
machines work, whether isolated or in their biological context.
When I am
not in a lab pipetting solutions, I enjoy reading about history and science,
street/candid photography, travelling, going to museums, writing, and learning
traditional Chinese characters.