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Ashley Paulson
Graduate Student
I was born in Hartford, Connecticut and shortly thereafter, my family moved to East Africa where we lived for 16 years while my father served with a non-profit organization. I attended boarding school in Kenya for 7 years before starting at Wheaton College in Illinois. I majored in Chemistry with a biochemistry emphasis and, ironically, graduated sans any biology classes. So I am excited to begin at Columbia!

During undergrad I was involved in molecular biology and electrophysiological research on staphylococcal alpha-hemolysin. Methods included site-directed mutagenesis to produce single cysteine mutations for attaching thiol-selective fluorophores, and immobilized metal affinity chromatography to purify the toxin. The eventual goal was single-molecule microscopy of pure alpha-hemolysin ion channels diffusing in lipid bilayers. My research interests are pretty broad, and include structural biology, and protein-DNA interactions, especially relating to transcription or translation. Research with implications for diseases affecting Africa would be a bonus.

Interests outside the classroom include music, tennis, Africa, COFFEE, pottery, and people. I taught Chemistry in Kenya for three months in 2008 and enjoyed my experience. My ultimate goal is to be a professor somewhere, possibly overseas.
Ashley Paulson
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