Amgen Scholars Summer Research Program

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Mentors 2019

Columbia University - Morningside Heights

Biological Sciences
Dr. Chloe Bulinski:
Function of the cytoskeleton during the cell cycle and differentiation
Dr. Harmen Bussemaker:
Data-driven predictive modeling of gene regulatory networks
Dr. Martin Chalfie:
Developmental genetics of identified nerve cells in C. elegans
Dr. Larry Chasin:
Pre-mRNA splicing; molecular and computational approaches
Dr. Lars Dietrich
Bacterial models for biological shape and pattern formation
Dr. Julio Fernandez:
Single molecule mechanics and engineering
Dr. Stuart Firestein:
Cellular mechanisms and signal transduction of olfaction
Dr. Iva Greenwald:
Genetic analysis of LIN-12/Notch signaling in C. elegans
Dr. Tulle Hazelrigg:
Epigenetic regulation of gene expression in Drosophila
Dr. Oliver Hobert:
Genetic programs that control neural development in C. elegans
Dr. John Hunt:
Structural biology of transmembrane transport
Dr. Songtao Jia:
Epigenetic regulation of the genome
Dr. Daniel Kalderon:

Hedgehog signaling in Drosophila development
Dr. Darcy Kelley:
Neurobiology of vocal communication and sexual differentiation
Dr. James Manley:
mRNA transcription, splicing, and processing
Dr. Carol Prives:
Cancer and p53
Dr. Ozgur Sahin:
Imaging and Modeling Biology at Physical Extremes
Dr. Brent Stockwell:
Diagramming disease networks with chemical and biological tools
Dr. Liang Tong:
Protein structure of enzymes involved in fatty acid metabolism
Dr. Alexander Tzagoloff:
Mitochondrial biogenesis
Dr. Jian Yang:
Structure, function and regulation of ion channels
Dr. Rafael Yuste:
Function of the cortical microcircuit

Biomedical Engineering
Dr. Tal Danino:
Engineering synthetic gene circuits in microbes
Dr. Edward Guo:
Bone tissue biomechanics
Dr. Clark Hung:
Cell and tissue engineering
Dr. Lance Kam:
Immune synapse affects T cell function
Dr. Kam Leong:
Nanotherapeutics, regenerative medicine, gene editing
Dr. Helen Lu:
Design of novel composite biomaterials for implantation
Dr. Barclay Morrison:
Neurotrauma and repair
Dr. Elizabeth Olson: (lab located at CUMC)
Auditory mechanics
Dr. Samuel Sia:
Microfabrication of tissues; diagnostic devices for global health
Dr. Gordana Vunjak-Novakovic: (lab located at CUMC)
Tissue engineering and stem cells

Dr. Ruben Gonzalez:
Ribosomal protein synthesis
Dr. Laura Kaufman :
Cancer cell invasion in novel biopolymer gels
Dr. Ann McDermott:
NMR studies of enzyme mechanism and membrane protein structure

Mechanical Engineering
Dr. Gerard Ateshian:
Tissue engineering and cell mechanics

Columbia University – Manhattanville Campus

Neuroscience, Mind Brain Behavior Institute
Dr. Randy Bruno:
Neuronal networks in the rodent whisker-barrel system
Dr. Michael Goldberg:
Spatial perception in monkeys and humans
Dr. Wes Grueber:
Mechanisms of dendritic morphogenesis and patterning
Dr. Elizabeth Hillman:
Optical imaging of living tissues
Dr. Minoree Kohwi:
Neural stem cell fate specification in Drosophila
Dr. Stavros Lomvardas:
Transcriptional regulation of Olfactory Receptor Choice
Dr. Richard Mann:
Homeotic gene function and their downstream targets in Drosophila
Dr. Carol Mason:
Axon guidance and synaptogenesis
Dr. Kenneth Miller:
Modeling of brain circuitry, and development
Dr. Franck Polleux:
EM reconstructions of the neuronal ER-mitochondrial network
Dr. Daniel Salzman:
Neural mechanisms underlying social buffering of emotion
Dr. Steven Siegelbaum:
Ion channel structure and function
Dr. Gary Struhl:
Drosophila developmental genetics
Dr. Sarah Woolley:
Neural basis and behavior of social communication
Dr. Charles Zuker:
The biology of mammalian taste

Columbia University – Health Sciences Campus

Biochemistry and Molecular Biophysics
Dr. Stephen Goff:
Retrovirus replication; tyrosine kinases & signal transduction
Dr. Samuel Sternberg:
Mechanism of bacterial CRISPR–Cas immune systems
Dr. Saaed Tavazoie:
Adaptation through transcriptional tuning of gene expression
Dr. Chaolin Zhang:
Neuronal RNA-regulatory networks

Genetics & Development
Dr. Tim Bestor:
The effect of "DNA methylation in sex cells"
Dr. Angela Christiano:
Genetics and immunology of skin anfd hair diseases
Dr. Alberto Ciccia:
Genomic instability in cancer and genetic disesases
Dr. Frank Costantini:
Genetics of mouse kidney development
Dr. Wayne Frankel:
Neuronal defects in genetic models of epilepsy
Dr. Laura Johnston:
Cell cycle control and growth during development
Dr. Gerard Karsenty:
The role of bone as an endocrine organ
Dr. Chao Lu:
Genome and epigenome regulation in cancer
Dr. Benjamin Ohlstein:
Intestinal stem cells in Drosophila
Dr. Rodney Rothstein:
Yeast genetics and cellular responses to DNA damage in cancer
Dr. Mimi Shirasu-Hiza:
The circadian clock's regulation of immune function in Drosophila
Dr. Debra Wolgemuth:
Genetics of male mammalian germ cell differentiation
Dr. Kelley Yan:
Instestinal stem cells in health and disease

Dr. Jonathan Barasch:
Kidney organogenesis

Medicine and Systems Biology
Dr. Xuebing Wu:
RNA-centric gene regulation in human cells

Microbiology and Immunology
Dr. Riccardo Dalla-Favera:
Genetics of human B cell tumors
Dr. Jonathan Dworkin:
Protein localization and chromosome segregation in Bacillus subtilis
Dr. Donna Farber:
The role of Memory T cells in protective immunity
Dr. David Fidock:
Plasmodium falciparum malaria parasite biology
Dr. Maxwell Gottesman:
Transcription termination in E. coli and bacteriophage
Dr. Yiping Han:
The role of the human microbiome in health and disease
Dr. Kang Liu:
Cellular and molecular events of the hematopoiesis of dendritic cells
Dr. Vincent Racaniello:
Picornavirus receptors and innate immune antagonism
Dr. Steven Reiner:
Mammalian immune response
Dr. Boris Reizis:
Immune System Development
Dr. Christian Schindler:
Cytokine signal transduction and its role in the immune response
Dr. Megan Sykes:
Bone marrow transplantation and immunology
Dr. Lorraine Symington:
Genetics and biochemistry of DNA recombination and repair

Dr. Robert Hawkins:
Gene regulation during classical conditioning
Dr. Serge Przedborski:
Mechanisms in neurodegeneration

Dr. Robert Hawkins:
Gene regulation during classical conditioning
Dr. Serge Przedborski:
Mechanisms in neurodegeneration

Pathology & Cell Biology
Dr. Cory Abate-Shen:
Treatments and detection of prostrate and bladder cancer
Dr. Swarnali Acharyya:
Metastasis cancer drug resistance microenvironment 
Dr. Dritan Agalliu:
Blood-brain barrier breakdown in multiple sclerosis
Dr. Julie Canman:
Molecular regulation and mechanics of cell division
Dr. Peter Canoll:
Glioma cell migration and proliferation
Dr. Helen Causton:
Learning from yeast
Dr. Alejandro Chavez:
Developing tools to study neurological disorders
Dr. Adolfo Ferrando:
Molecular mechanisms of proliferation and survival of leukemic cells
Dr. James Goldman:
Neuron and glial cell fate determination
Dr. Lloyd Greene:
Research on neurodegeneration and brain tumors
Dr. Rebecca Haeusler:
Cholesterol metabolism in diabetes
Dr. Steve Kernie:
The role of stem cells in neuronal repair
Dr. Tae-Wan Kim:
Molecular mechanisms in Alzheimer's disease
Dr. Kenneth Olive:
Translational therapeutics in pancreatic cancer
Dr. David Owens:
Epidermal stem cells
Dr. Liza Pon:
Role of the actin cytoskeleton
Dr. Andrew Sproul:
Novel human stem cell models of Alzheimer’s
Dr. Ira Tabas:
Role of Tregs in efferocytosis and atherosclerosis
Dr. Carol Troy:
Molecular mechanisms of neuronal death
Dr. Harris Wang:
Probiotic Engineering
Dr. Hynek Wichterle:
Human Nervous system development
Dr. Shan Zha:
DNA break repair
Dr. Xin Zhang:
FGF signaling in eye development

Dr. Meenakshi Rao:
Enteric nervous system and gastrointestinal function
Dr. Kimara Targoff:
Zebrafish modeling of cardiac development 

Dr. Alice Prince:
Bacterial induction of cytokine signaling in epithelial cells

Dr. Maura Boldrini:
Human brain neuroplasticity in stress and disease
Dr. Christine Denny:
Optogenetic dissection of memory in Alzheimer’s 
Dr. René Hen:
Neurobiology of learning and memory
Dr. Martin Picard:
Mitochondrial mechanisms of stress psychobiology
Dr. Stephen Rayport:
Dr. David Sulzer:
Synaptic plasticity and diseases of the brain

Dr. Jeffrey Bruce:
Brain tumors

New York State Psychiatric Institute
Dr. Jonathan Javitch:
Structure, function & regulation of receptors and transporters