Evren U. Azeloglu

Doctoral Student, Department of Biomedical Engineering

Education
B.S., Mechanical Engineering, State University of New York Stony Brook, 2002
M.S., Biomedical Engineering, State University of New York Stony Brook, 2004

Research Summary
Mechanical interactions of cells with the extracellular matrix or their neighboring cells play an important role in tissue regeneration and remodeling. Atomic force microscope (AFM) can be used to probe cells for mechanical characterization, live imaging and more. We use AFM to study a number of cells (myocytes, alveolar cells, neurons etc.) either in their natural environments or in engineered-tissue-constructs. In addition to standard modes of indentation, we also develop novel AFM-based mechanical testing platforms such as cell compression chambers and micro-rheology platforms with the use of custom microfabricated AFM-tips.

Recent Publications
Kelly DJ, Azeloglu EU, Kochupura PV, Sharma GS, Gaudette GR. Accuracy and reproducibility of a subpixel extended phase correlation method to determine micron level displacements in the heart. Med Eng Phys. 2007; 29(1): 154-62.

Azeloglu EU, Yun YH, Saltman AE, Krukenkamp IB, Chiang FP, Chen W, Gaudette GR. High resolution mechanical function in the intact porcine heart: mechanical effects of pacemaker location. J Biomech. 2006; 39(4): 717-25.

Kochupura PV, Azeloglu EU, Kelly DJ, Doronin SV, Badylak SF, Krukenkamp IB, Cohen IS, Gaudette GR. Tissue-engineered myocardial patch derived from extracellular matrix provides regional mechanical function. Circulation. 2005; 112: I-144 - I-149.

Gaudette GR, Krukenkamp IB, Azeloglu EU, Saltman AE, Lense M, Todaro J, Chiang FP. Effects of ischemia on epicardial deformation in the passive rabbit heart. J Biomech Eng. 2004; 126(1): 70-5.

Teaching
BMEN E4002 Quantitative Physiology II -- Spring '05, '06, '07 (Teaching Assistant)
BMEN E3810 Biomedical Engineering Lap I -- Spring '05 (Teaching Assistant)

Acknowledgment
My research has been funded by the Stony-Wold Herbert Fund.