Synthetic Biology aims to engineer artificial pathways in cells both to test fundamental notions of how complex biological networks function and to develop new technologies for the treatment of disease. Moving beyond advances in the last century for the synthetic manipulation of biomolecules in vitro, my laboratory is creating conceptually new approaches for the modification of biomolecules in a living cell. As opposed to designing molecules that can be added to the cell with minimal perturbation of its natural functions, our approach is to design molecules capable of co-opting the cell’s own highly evolved and integrated synthetic machinery (evolution and translation) for production of the modified biomolecules in vivo. Finally, we are using these new synthetic methods to develop tools for live cell imaging.
- Joshua Cho has joined the lab through the Integrated Program in Cellular, Molecular and Biomedical Studies...Welcome Josh!
- Congratulations to Nili, Miguel, and Sonja on their paper in Science Advances!
- Congratulations to Nina on beginning her PhD at the University of Washington!
- Congratulations to Joe on receiving an NSF graduate research fellowship!
- Congratulations to Dr. Jimenez on defending his thesis and beginning a postdoc in Steve Langer's lab at MIT Koch Institute!
- Congratulations to Andrew and Zhixing on their paper in Chemical Communications!
- Congratulations to Dr. Ng on defending his thesis and beginning as a data scientist at Genetic Intelligence!
- Congratulations to Dr. Sanguineti on defending her thesis and beginning as an assistant program director at Brooklyn College!
- Congratulations to Dr. Patenode on defending her thesis and beginning as a program manager at Womensphere Foundation!
- Congratulations to Sean on receiving an NSF graduate research fellowship!
- Congratulations to Andrew and Annie on their paper in Nature Methods!