Instrumentation

NMR Techniques for Structural Determination

The following techniques are implemented. They are grouped by the type of information provided. Others are available upon request.

H-H connectivity -through J coupling

COSY
COSY-DQF
TOCSY-2D
selective TOCSY-1D

J measurement (H-H)

COSY-DQF
E. COSY
H-H Homonuclear decoupling
Spectral simulation (Xsim program, gNMR)

H-H spatial proximity

Carbon-proton connectivity - through J coupling

HMQC-HSQC - direct correlation - one bond
HSQC-TOCSY - carbon resolved TOCSY
HMBC - long range correlation - 2 to 3 bond. Accordion method for reduced dependence on coupling values
ADEQUATE - proton detected INANEQUATE- long range correlation

J measurement (C-H long range)

Exside

Water suppression

watergate
presaturation

Exchange - Relaxation

2D EXESY (NOESY)
selective magnetization transfer 1D
T1 measurement

Heteronuclear NMR

NMR spectra of nuclei such as carbon, phosphorus, fluorine, deuterium, nitrogen, etc...

Diffusion

diffusion measurements, size determination

Solid-State-NMR

CP-MAS