Synthetic Organic Chemistry, Neuroscience, and Molecular Imaging
We develop new molecular imaging agents for visualization of metabolism and neurotransmission in the brain. We have recently introduced novel agents termed Fluorescent False Neurotransmitters that for the first time enable optical imaging of neurotransmitter release at individual synapses. The molecular design is greatly aided by new synthetic methods developed in our laboratory. We are particularly interested in the catalytic C-H bond functionalization processes.