Jonathan A. Javitch attended Stanford University
where he obtained a B.S. and M.S. in Biological Sciences in 1980.
1986 he completed the joint M.D.-Ph.D. program at the Johns Hopkins
University School of Medicine, where as a graduate student with
Dr. Solomon Snyder he demonstrated that a key step in the Parkinson’s-like
neurotoxicity of MPTP is the uptake of its metabolite MPP+ by the
dopamine transporter. After graduating from Hopkins, Dr. Javitch
completed a medical internship and psychiatric residency at the
Columbia Presbyterian Hospital and the New York State Psychiatric
Institute. He did postdoctoral work on the structure of dopamine
receptors with Dr. Arthur Karlin at Columbia University. Dr. Javitch
currently is a tenured Associate Professor of Psychiatry and Pharmacology
in the Center for Molecular Recognition at Columbia University.
His laboratory focuses on understanding the structure and function
of G-protein coupled receptors and neurotransmitter transporters,
with a particular focus on dopamine receptors and transporter, the
targets for antipsychotic drugs and cocaine, respectively.