Qiao Lin
236 S. W. Mudd, Mail Code: 4703
Phone: +1 212-854-1906
Fax: +1 212-854-3304
Email:
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Qian Lin conducts research in the area of microelectromechanical systems (MEMS) with applications to biology and medicine. Current research is focused on designing and creating micro/nanosystems; in particular, microelectromechanical systems (MEMS) and micro/nanofluidic systems, for controlling the motion and measuring the dynamic behavior, such as conformational transitions, and interactions and reactions of biomolecules in solution. The goal of these systems is primarily to facilitate understanding of fundamental biophysical phenomena, and to enable practical biomedical applications. These systems not only will allow automated, high-throughput analysis of biological systems with drastically reduced sample consumption but may enable novel biophysical investigations not attainable by conventional instruments.
Specific research thrusts involve modeling and understanding the physics of micro/nanofluidic devices and systems, exploiting polymer micro- and nanotechnologies for biofluid and biomolecular manipulation, and integrating MEMS sensors with microfluidics for measuring physical properties of biomolecules.
Publications
Q. Lin, Y. Xu, F. Jiang, Y.C. Tai and C.M. Ho, "A Parametrized Three-Dimensional Model for MEMS Thermal Shear-Stress Sensors," J. of Microelectromechanical Systems , 14: 625-633, 2005.
G.D. Ehrlich, P. Stoodley, S. Kathju, Y.J. Zhao, B.R. Mcleod , N. Baliban, F.Z. Hu, N.G. Sotereanos, J.W. Costerton, P.S. Stewart, J.C. Post, and Q. Lin, "Engineering Approaches for the Detection and Control of Orthopedic Biofilm Infections," Clinical Orthpaedics and Related Research , in press.
Q. Lin, J.W. Burdick and E. Rimon, "Constructing Minimum Deflection Fixturing Arrangements Using Frame Invariant Norms," IEEE Trans. on Automation Science and Engineering , in press.
Y. Wang, Q. Lin and T. Mukherjee, "A Model for Complex Electrokinetic Passive Micromixers," Lab on a Chip , in press.
Y. Wang, Q. Lin and T. Mukherjee, "Composable Behavioral Models and Schematic-Based Simulation of Electrokinetic Lab-on-a-Chips," IEEE Trans. on Computer-Aided Design of Integrated Circuits and Systems, Special Issue on Design Automation Methods and Tools for Microfluidics-Based Biochips , in press.
Y. Xu, C.W. Chiu, F. Jiang, Q. Lin and Y.C. Tai, "A MEMS Multi-Sensor Chip for Flow Sensing," Sensors and Actuators, A: Physical , in press.
Y. Xu, Q. Lin, G. Lin, F. Jiang, and Y.-C. Tai, "MEMS Underwater Shear-Stress Sensors," J. of Micromechanics and Microengineering , in press.
B. Yang, B. Aksak, Q. Lin, and M. Sitti, "Compliant and Low-Cost Humidity Nanosensors using Nanoporous Polymer Membranes," Sensors and Actuators, B: Chemical , in press.
G.D. Ehrlich, F.Z. Hu, Q. Lin, J.W. Costerton, and J.C. Post, "Intelligent Implants to Battle Biofilms," ASM News, American Society for Microbiology , 70: 127-133, 2004.
Q. Lin, J.W. Burdick and E. Rimon, "Computation and Analysis of Compliance in Grasping and Fixturing," IEEE Trans. on Robotics , 20: 651-667, 2004.
Q. Lin, F. Jiang, X. Wang, Y. Xu, Z. Han, Y.C. Tai, J. Lew and C.M. Ho, "Experiments and Simulations of MEMS Thermal Sensors for Wall Shear Stress Measurements in Aerodynamic Control Applications," J. of Micromechanics and Microengineering , 14: 1640-1649, 2004.
S. Liu, A. Davidson and Q. Lin, "Simulation Studies on Nonlinear Dynamics and Chaos in a MEMS Cantilever Control System," J. of Micromechanics and Microengineering , 14: 1064-1073, 2004.
Y. Wang, Q. Lin and T. Mukherjee, "System-Oriented Dispersion Models of General-Shaped Electrophoresis Microchannels," Lab on a Chip , 4: 453-463, 2004.
Y. Wang, Q. Lin and T. Mukherjee, "A Model for Joule Heating-Induced Dispersion in Microchip Electrophoresis," Lab on a Chip , 4: 625-631, 2004.
J. Xie, J. Shih, Q. Lin, B. Yang and Y.C. Tai, "Surface Micromachined Electrostatically Actuated Micro Peristaltic Pump," Lab on a Chip , 4: 495-501, 2004.
B. Yang, G.C. Lopez, A.J. Rosenbloom and Q. Lin, "Design and Rapid Fabrication of a Microfluidic Fraction Collector," Int. J. of Nonlinear Sciences and Numerical Simulation , 3 (3-4): 267-272, Sp. Iss. SI, 2002.
S. Wu, Q. Lin, Y. Yuen and Y.C. Tai, "MEMS Flow Sensors for Nano-fluidic Applications," Sensors and Actuators A: Physical , 89: 152-158, 2001.
Q. Lin, J.W. Burdick and E. Rimon, "A Stiffness-Based Quality Measure for Compliant Grasps and Fixtures," IEEE Trans. on Robotics and Automation , 16: 675-688, 2000.
Q. Lin and J.W. Burdick, "Objective and Frame-Invariant Kinematic Metric Functions for Rigid Bodies," Int. J. of Robotics Research , 19: 612-625, 2000.