Search:
Columbia University Medical Center, Department of Pediatrics, Pediatric Infectious Disease Divisionan image of Bacteria

Adam J. Ratner, MD MPH

EDUCATION

Yale University, BA,1993
Columbia University School of Public Health, MPH, 1997
Columbia University College of Physicians & Surgeons, MD, 1998

ACADEMIC TITLE

Assistant Professor of Pediatrics and Microbiology

SPECIALITY

Microbial Pathogenesis
Bacterial Toxins
Innate Immunity

RESEARCH AND CLINICAL SUMMARY

We investigate the pathogenesis of infectious diseases, with a focus on bacterial diseases affecting children. Please see the laboratory website (http://www.ratnerlab.org) for details.

OFFICE INFORMATION:

Adam J. Ratner, MD, MPH
650 West 168th Street.
Black Building 421
New York, NY 10032
Tel: (212) 305-9807
Fax: (212) 342-5218
Email: ar127@columbia.edu

SELECTED PUBLICATIONS

  • Ratner AJ, Lysenko ES, Paul MN, Weiser JN. Synergistic proinflammatory responses induced by polymicrobial colonization of epithelial surfaces. Proc Natl Acad Sci, 2005; 102: 3429-34.
  • Lysenko ES, Ratner AJ, Nelson A, Weiser JN. The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfaces. PLoS Pathog 2005; 1: e1.
  • Shah SS, Ratner AJ. Trends in invasive pneumococcal disease-associated hospitalizations. Clin Infect Dis 2006; 42: e1-5.
  • Ratner AJ, Hippe KR, Aguilar JL, Bender MH, Nelson AL, Weiser JN. Epithelial cells are sensitive detectors of bacterial pore-forming toxins. J Biol Chem 2006; 281: 12994-8.
  • Nelson AL, Roche AM, Gould JM, Chim K, Ratner AJ, Weiser JN. Capsule enhances pneumococcal colonization by limiting mucus-mediated clearance. Infect Immun 2007; 75: 83-90.
  • Ratner AJ, Aguilar JL, Shchepetov M, Lysenko ES, Weiser JN. Nod1 mediates cytoplasmic sensing of combinations of extracellular bacteria. Cell Microbiol 2007; 9: 1343-1351.