James F. Bender Professor
Ph.D., Brown University, 1970
General Area of Research
Physiological and psychophysical studies of human visual perception
Tests of explanations/models of normal and abnormal retinal and optic nerve activity.
Our laboratory is interested in the physiological bases of both normal and abnormal visual processing. Using both behavioral (psychophysical) and electrophysiological techniques, we study the vision of both normal individuals and patients with diseases of the retina or ganglion cell/optic nerve.
We record small (nanovolt range) electrical signals from the human eye (retina) and brain (visual areas of cortex). Using state-of-the-art technology, we can obtain these small responses from local regions of the retina and cortex. These techniques allow us to study spatially localized activity in the eye and the brain.
With these techniques, we can test models of normal and abnormal vision. For example, we are currently testing a model that relates the activity in the human visual cortex (V1) to recordings from single cells of animals reported by others. In addition, we are testing explanations for the effects of glaucoma and multiple sclerosis on retinal ganglion cell and optic nerve activity.
Hood, D.C., Yu, A.L., Zhang, X., Albrecht, J., Jagle, H., and Sharpe, L.T. (2002). The multifocal visual evoked potential and cone isolating stimuli: Implications for L- t M-cone ratios and normalization. Journal of Vision, 2, 178-189.
Hood, D.C., and Greenstein, V.C. (2003) The multifocal VEP and ganglion cell damage: applications and limitations for the study of glaucoma. Progress in Retinal and Eye Research, 22, 201-251.
Courses Frequently Taught
1190 Amsterdam Avenue MC: 5501
New York, NY 10027