Existing development eliminated most of the natural vegetation and wildlife within the Fifth Avenue area boundaries. The remaining vegetation consists of small patches of mowed lawn and a mixture of ornamental and native flowers, shrubs and trees.

The wildlife found within the boundaries of the Fifth Avenue area include those typically associated with an urban environment such as squirrels, opossums, raccoons, feral cats, various rodents, gulls, pigeons, starlings, and sparrows.

The area does not contain any threatened or endangered vegetation or wildlife.