| SECRETION
OF THYROID HORMONE |
|
|
|
|
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| ENDOCYTOSIS
OF |
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| ‘COLLOID’
IN FOLLICLE BY |
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| PSEUDOPOD |
||||
| 4 |
|
|
|
| IODINATION
OF THYROGLOBULIN |
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| BY THYROID
PEROXIDASE |
||
| TG |
| 3 |
| TG |
| TG |
| I |
| 5 |
|
|
|
| FUSION
OF PHAGOSOME |
||
| WITH
LYSOSOMES |
||
| TG |
| 6 |
| TG |
|
|
|
|
|
|
|
|
|
| DEGRADATION |
||||||||
| AND |
||||||||
| RECYCLING |
||||||||
| OF
MIT/DIT |
||||||||
| BY
DEIODINASES |
||||||||
|
|
| DEGRADATION
OF |
|
| THYROGLOBULIN |
|
| 7 |
|
|
|
| FREE
THYROXINE RELEASED FROM |
||
| PROTEIN INTO CYTOPLASM |
||
| T4 |
| 2 |
| 8 |
|
|
|
|
|
| IODIDE
UPTAKE |
||||
| BY Na/I |
||||
| SYMPORTER |
||||
|
|
| “DIFFUSION”
OF THYROXINE |
|
| THROUGH
CELL MEMBRANE |
|
| > |
| > |
| > |
| Additional
metabolism?? |
|
|
|
| IODIDE IN |
||
| ECF~20nM |
||
| 1 |