| REGULATION
OF TRANSCRIPTION BY NON-STEROIDAL HORMONES |
| NUCLEUS |
| - |
| NO HORMONES |
| RX |
| R |
| NO
TRANSCRIPTION |
|
|
|
| HORMONE-RESPONSIVE |
||
| TARGET GENES |
||
| N |
| C |
| HRE |
|
|
|
|
|
|
|
| RETINOID X RECEPTOR SUBUNIT (RX) |
||||||
| REPRESSES
TRANSCRIPTIONAL |
||||||
| ACTIVATION
BY HORMONE |
||||||
| RECEPTOR (R) |
||||||
| PLUS
HORMONES |
| NUCLEUS |
| + |
| TRANSCRIPTION |
|
|
|
| HORMONE-RESPONSIVE |
||
| TARGET GENES |
||
|
|
|
|
|
| VITAMIN D |
||||
| RETINOIC
ACID |
||||
| THYROID
HORMONE |
||||
| HRE |
|
|
|
|
|
|
|
| HORMONE
BINDING |
||||||
| RELIEVES
REPRESSION |
||||||
| BY
RETINOID X |
||||||
| RECEPTOR |
||||||