| 1,2-DAG |
|
|
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| PHOSPHATIDYLINOSITOL |
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| CYCLE |
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| PI 3,4 -P2 |
|
|
|
| PROTEIN
KINASE C |
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| ACTIVATION |
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|
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| PHOSPHOLIPASE
C |
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| (PLC)
MEDIATED |
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| PI
HYDROLYSIS |
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| IS
STIMULATED BY |
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| MANY
HORMONES |
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| PI 3,4,5-P3 |
| PI 3-KINASE |
| INSULIN
ACTION |
| PLC |
| PI |
| PI 4-P |
| PI 4,5-P2 |
| PHOSPHORYLATION |
| RESYNTHESIS |
| DEGRADATION |
| Li + |
| IP2 |
| I |
| IP |
| IP3 |
|
|
|
| Li + BLOCKS |
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| RESYNTHESIS |
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|
|
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|
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| CALCIUM
RELEASE |
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| FROM
ER VIA LIGAND |
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| GATED
CHANNEL |
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