PHOSPHOLIPASE C ISOFORMS

PLCd

N

PH

EF

X

Y

C

CATALYTIC SITES

REGULATED  BY Gaq

PLCg

N

X

SH2

Y

C

PH

EF

SH2

SH3

REGULATED BY TYROSINE  PHOSPHORYLATION

PLCb

N

PH

EF

X

Y

C

CATALYTIC SITES

REGULATED  BY Gaq