REGULATION OF PLASMA GLUCOSE BY INSULIN AND GLUCAGON
P
glucose
PARACRINE INHIBITION OF ISLETS OF
LANGERHANS BY INSULIN
TARGET TISSUES
(liver, muscle, adipose, etc.)
GLUCAGON
t½ approx 10 min
INSULIN
t½ approx 5 min
INSULIN
SECRETION
GLUCOSE:
- SYNTHESIS
- MOBILIZATION
GLUCAGON
SECRETION
P
glucose
GLUCOSE:
- UPTAKE
- UTILIZATION
- STORAGE
PANCREAS
a
cell
PANCREAS
b
cell