PowerPoint Presentation - Low Lectures

Thyroglobulin

I

I

Tyr

3,5,3�5�-tetraiodothyronine

I

I

Tyr

I

I

I

Tyr

O

T

CH2CHCOOH

I

I

I

Tyr

NH2

+

NH2

I

4

I

I

Tyr

CH2CHCOOH

NH2

CH2CHCOOH

3,3�,5�-Triiodothyronine (reverse T3)

NH2

Tyr

I

I

I

Tyr

O

rT3

I

3,5,3�-Triiodothyronine (T3)

I

I

Tyr

I

I

I

Tyr

O

T4

I

T3

Tyr

I

I

I

Tyr

O

I

5�- deiodination

5-deiodination

CH2CHCOOH

�ACTIVATION� PATHWAY

�DEACTIVATION� PATHWAY

NH2

STEP 3 DEIODINATION

SELENODEIODINASES