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| Summary:
MDR-Transduced |
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| HSC in
NOD-SCID Mouse |
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| l | MDR
transduction of human HSC |
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| achieved |
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| l | Transduction
efficiency comparable |
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| to
that of clinical trial:1-10% of human |
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| cells |
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| l | Conditions:
5 cytokines, no |
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| polybrene,
Retronectin, multiple viral |
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| exposures |
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