| Factor
8 and 9 Deficiencies |
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| l | Hemophilia
A and B |
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| l | Factor
8 and 9 concentrates and |
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| recombinant
proteins effective |
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| l | Factor
8 and 9 genes in AAV or adenovirus |
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| injected
into muscle raises levels in mice |
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| and
dogs |
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| l | Human
Factor 9 AAV trial into muscle |
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| underway
(High) |
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| l | Evidence
for immune responses |
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