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| Calcium Dependent Inactivation |
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| of
L-type Ca2+ Channels |
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| • | Calmodulin is the Ca2+ sensor |
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| • | CaM is pre-associated with a1C |
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| • | The IQ motif is the effector domain in a1C |
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| • | The EF-hand is a structural, non Ca2+- |
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| sensing domain |
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