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Three criteria
need to be satisfied in order to
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identify a
characteristic as a risk factor:
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1. the factor must be observed to covary
with the disease
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i.e., the factor must be statistically
associated with the
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development of
the disease
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or equivalently,
the frequency of disease must be observed to
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differ by
category or value of the factor
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2. the presence of the risk factor ( or a
relevant change in
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the risk factor)
must precede occurrence of the disease
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