Notes
Outline
"Fluoride Varnish in a Pediatric..."
Fluoride Varnish in a Pediatric Practice
Created by
W. Edward Gonzalez D.M.D.
OMNII Oral Pharmaceuticals ®
The Preventive Care Consultants
OMNII “Firsts In Dentistry”
OMNII GelÔ
5% Neutral Sodium Fluoride Varnish
May 2000 - Cover Story
“Off Label” Efficacy
Tewart & Associates reported that after 2.5 years, the fluoride varnish resulted in a higher percentage of caries reduction than did the 2 % sodium fluoride solution and the 1.23% acidulated phosphate fluoride gel
Source: JADA, MAY, 2000
“Off Label” Efficacy
Numerous randomized clinical trials conducted outside the United States point to the efficacy and safety of fluoride varnishes as a caries-preventive agent
Source: JADA, MAY, 2000
Other Feature Articles
March 2001,Washington, D.C.
“The overall preventive effect of professional fluoride gel treatments on caries increments between children treated and children not treated was between 18 and 25 percent. Clinical investigation of the application of fluoride varnish to permanent teeth of children provided preventive effects of between 25 and 50 percent”.
R. Gary Rozier, D.D.S
Worldwide Usage
Developed in late 1960s and early 1970’s
Numerous studies show efficacy
Used extensively in Europe and Canada as a primary preventive agent
92% of Denmark’s municipal preventive programs use Fluoride Varnish exclusively
As much as 75% reduction in decay*
* Goran Kock et. Al.1975
Fluoride Varnishes
Available In The U.S.
Duraphat® (Colgate Oral Pharmaceuticals)  5% NaF - 10 ml tube
Duraflor®  (Medicom® Inc.)           5% NaF - 10 ml tube
Fluor Protector (Ivoclar-Vivadent)  1% Difluorsilane
(unit-dose)
CavityShield® (OMNII )   5% NaF(unit-dose)
Advantages of Fluoride Varnish
Neutral taste
Apply in less than one minute
Does not require special equipment or the need for a prophylaxis prior to application
Safety
Application in Orthodontics
As much as 50% reduction in demineralization (1)
Special applications for handicapped, mentally and medically compromised patients
Delay caries progression
1. M.A. Todd et al., “Effect of fluoride varnish on demineralization adjacent
to orthodontic brackets,” American Journal of Orthodontics and Dentofacial
Orthopedics (August 1999): 159-167.
Neutral Taste
CavityShield® sets on contact with saliva
CavityShield® is sweetened with
Xylitol
Application
No need for prophy prior to application
Yellow tint for application control
“Tooth brush cleaning”
Applicator brush provided for convenience and cost savings
Unit-dosed for asepsis control
Color
Safety Application/Convenience
Application Safety
Dosage Safety
Inherently Inconsistent
Dosage Delivery
Product Safety
CavityShield®
1 ml = 50 mg sodium fluoride = 22.6 mg F
22,600 ppm F
Dosage Applied
0.25 ml for primary dentition
0.40 ml for mixed dentition
0.65 ml for permanent dentition
Product Safety
Following application of varnish on four children, ages 4, 5, 12 and 14: “Peak plasma fluoride concentrations of 3.2 to 6.3 micromolar were found within two hours of treatment… These levels were comparable with those found after brushing with a fluoridated toothpaste (3.63 +/- 0.45 mmol/h) or after ingesting a 1-mg F tablet (4.47 +/- 0.47 mmol/h)  and were considerably lower than those reported for APF gels (16 to 76 mmol/h)
Easy Application
Site Specific Application
Interproximal Application
Orthodontic Application
50% Reduction
Demineralized Enamel
Conservative Treatment of White Spot Lesions
White Lesions Not
Visible on X-ray
White Spot Treatment
Other Current
Treatment Modalities
Severe Early Childhood Caries
(Arrest progression to time when child will tolerate needed treatment)
Placement under the flap of partially erupted six or twelve year old molars
Glass Ionomer
Recharge Fluoride Content
Fluoride Treatments
for the Future
Care After Treatment
Directions For Care After Treatment With CavityShield® Fluoride Varnish.
After the application of CavityShield® you will feel a coating and may notice a difference in color while the varnish remains on your teeth. To obtain the maximum benefit during the 4 - 6 hour treatment period, we ask that you take the following care after you leave our office:
 Do not remove CavityShield® by brushing or flossing for at least 4 - 6 hours.
 If possible, wait until tomorrow morning to resume normal oral hygiene.
 Eat a soft food diet during the treatment period.
 Avoid hot drinks and products containing alcohol (i.e.: beverages, oral
rinses, etc.) during the treatment period.
A thorough brushing and flossing will easily remove any remaining CavityShield®. Your teeth will return to the same shine and brightness as before the treatment.
Cost Per Application*
CavityShield® Unit-Dose (0.25 ml - 32 packages) $0.91
Duraphat (10 ml tube) $1.48
Duraflor (10 ml tube) $1.54
Average cost per application for gel or foam in disposable tray is between $.55 and $1.18.
* Includes cost of brush, if not provided. Retail price comparison
(Colgate and Schein) as of 5/2001.
OMNII Oral Pharmaceuticals®