•Phox2b: Transcription factor expressed by the most primitive of
the crest-derived cells that colonize the gut.
•Sox10:
Transcription factor: required early in development.
•Ret, its co-receptors, and ligands: Receptor tyrosine kinase
activated first by GDNF, and then NTN.
•EDN3 and EDNRB: collaborates with Ret and needed by
non-crest-derived cells of colon
•SIF1:
Encodes Smad protein, involved in BMP signaling