Facial and palatal
development
Timeline for development
Contributions to the
external face
Contributions to external
face
Slide 5
Oropharyngeal membrane
(buccopharyngeal, oral)
Disintegration of
oropharyngeal membrane
Stomodeum at 4 weeks
Facial processes
(prominences)
Connexin (gap junctions!)
expression in the facial processes at different stages of chick face
development. These are the cell groups that contribute most to the overall
expansion of the facial processes.
Development external face
(4-5 wks)
Development external face
(6-8 wks)
Face development -
animation
Dimensional changes (4-6
wks)
10-fold linear increase in
size !
Merging
Differential mesenchymal proliferation.
Elimination of groove.
Merging with epithelial
inclusion
Sites of potential facial
clefts
Fusion
Contact and fusion of epithelium-covered surfaces. Removal of epithelium
Fusion in primary and
secondary palate development
Fate of fused epithelium
Development of nose
Slide 23
Slide 24
Slide 25
Oronasal membrane
Primary (primitive) palate
Development of primary and
secondary palate
Intrinsic factors in the
successful development of the secondary palate: increase in size of palatal
processes
Secondary palate
development
Slide 31
Horizontalization of
palatal processes
Factors contributing to the
horizontalization of the palatal processes
Slide 34
Slide 35
Factors contributing to the
successful fusion of the secondary palate: the medial edge epithelium (MEE)
Slide 37
Slide 38
Completion of palate
formation
Sites of potential palatal
clefts