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|
|
Normal implantation: Larsen, WI, Human Embryology, 3rd
ed., Churchill Livingston, NY (2001), p. 22
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Ectopic sites: Carlson 3rd ed., p. 60
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|
Endometrium:
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|
Anatomy of uterus.
|
|
Blastocyst 0.1 - 0.2mm
diameter. Mucosa 5mm, Slit-like
Lumen of uterus 1mm anterior to posterior
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Fundus - Dorsal wall
|
|
More than 3/4 (78%)
fertilized oocytes do not reach term.
|
|
62% conceptions lost in
first 12 weeks.
|
|
Ectopic (1%) 0.25-1.4% of
all pregnancies - of those 95% are tubal
|
|
Tubal - pelvic
inflammatory disease; rupture of
wall partly because there are no uterine NK cells as there are in the
endometrium to induce apoptosis in trophoblast that invades too deep
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|
cervical = placenta
praevia
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