| Wolffian
Duct>>? |
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| • | Changes the
surrounding duct cells to express |
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| Pax-2. |
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| • | Pax-2 is required
for all subsequent steps. |
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| • | As the Wolffian
duct advances caudally, |
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| nephrons appear
on either side of the duct. The |
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| nephrons form
perpendicular to the cord. The |
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| are called
‘mesonephric tubules’. 20-30 tubules |
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| form. It is
functional in amphibia and fish, but in |
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| mammals only the
cranial 4-6 attach to the |
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| Wolffian duct,
and the rest will degenerate. |
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