Hair Cells: Tricks to enhance response
• Inner hair cells: MAIN SOURCE of afferent signal in
auditory (VIII) nerve. (~ 10 afferents per hair cell)
• Outer hair cells: primarily
get EFFERENT inputs.
Control stiffness, amplify
membrane vibration.
(5,000,000 X range)
• To enhance frequency tuning:
– Mechanical resonance of hair bundles: Like a tuning fork, hair
bundles of cells near base of cochlea are short and stiff, vibrating
at high frequencies; hair bundles near the tip of the cochlea are
long and floppy, vibrating at low frequencies.
– Electrical resonance of cell membrane potential (in mammals?)
– An AMAZING feat of development.
• Synaptic transmission speed (10 ms):
– Synaptic density: for speed? (normal synapse: 1 to 100s of ms)