| Peptidoglycan
Biosynthesis |
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| • | Synthesis
of water soluble, nucleotide-linked |
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| precursor
in the cytoplasm |
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| • | Transfer
of precursors from nucleotide to the |
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| bactoprenol
membrane lipid (pivot), followed by |
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| the
addition of substituents |
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| • | Addition
of the prefabricated block to a linear |
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| glycan
chain on the far side of the membrane |
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| • | Cross-linking
to an adjacent chain via |
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| transpeptidation
(enzymes are called penicillin- |
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| binding
proteins) |
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