 |
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|
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| w |
Goal: Correct
bleeding time and Factor VIII level
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|
| w |
Ideal test for
monitoring efficacy of therapy never
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|
documented
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|
| w |
Treatment
usually needed only for surgery or major
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trauma
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| w |
DDAVP
(Desmopressin - 0.3 μg/kg by infusion
|
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|
• |
Often effective
for Type I; tachyphylaxis develops
|
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|
|
• |
Ineffective in
Type IIa; relatively contraindicated in Type IIb
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|
• |
MUST
TEST FOR EFFICACY PRIOR TO USE
|
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| w |
Cryoprecipitate
- 1000-1200 units every 12 hours for
|
|
|
Types I & II
vWD; 2000-2400 units every 12 hours for
|
|
Type III vWD
|
|
|
| w |
Factor VIII
concentrate - Do not use, except:
|
|
|
|
• |
Humate-P (only
one containing significant vWF)
|
|
