Treatment of Syphilis
Latent Syphilis
Recommended regimen
   Benzathine penicillin G 2.4 million units IM at
one week intervals x 3 doses
Penicillin allergy*
   Doxycycline 100 mg orally twice daily
             or
   Tetracycline 500 mg orally four times daily
    Duration of therapy 28 days; close clinical and serologic
    follow-up; data to support alternatives to pcn are limited