Contraception in the Community

U.S. Pregnancies:
Unintended vs. Intended

Adolescents Who Have Had Intercourse

The Need for Contraception
Unintended Pregnancies (%) by Age

The Need for Contraception
Pregnancies Ending in Abortion by Age

Adolescent Pregnancy
An International Perspective—Developed Countries

Adolescents Delay Seeking Medical Contraceptive Services

FDA Advisory Committee’s Recommendation on Delay of Pelvic Exam

Adolescents’ Contraception at First Intercourse

Method Use, Last Intercourse
Young Women, 14 to 22 years old

Properties of Contraceptives
Desired by Women

Optimizing Patient Choices

Common Contraceptive Choices

Current Trends in Contraception

Oral Contraceptives

Levonorgestrel and Norethindrone
Plasma Levels After Single Oral Dose

Drugs That Decrease the Effectiveness of OCs

Drugs That Do Not Decrease the Effectiveness of OCs

Noncontraceptive Benefits of OCs

Noncontraceptive Benefits of OCs

Studies Show OCs Reduce Risk of Ovarian Cancer

Ovarian Cancer and OCs
Risk Reduction by Years of Use

OCs Protect Against Ovarian Cancer After Discontinuation

OCs Reduce Risk of Ovarian Cancer in High-Risk Women

Studies Show OCs Reduce Risk
of Endometrial Cancer

OCs Reduce Risk of Endometrial Cancer By Years of Use

OCs Protect Against Endometrial Cancer After Discontinuation

Ovarian and Endometrial Cancers and Low-Dose OCs

Bone Mass and OC Use
Studies Examining Association

Higher Bone Density
More Likely in OC Users

Higher Bone Density
Association With Longer OC Use

Do 20 µg EE OCs Increase Bone Mineral Density?

Acne

Acne Improvement with OCs

Reductions in Inflammatory
Lesion Counts at Cycle 6*
 EE 35 µg/NGM (Ortho Tri-Cyclen) vs. Placebo

Reductions in Total Lesion Counts at Cycle 6*
 EE 35 µg/NGM (Ortho Tri-Cyclen) vs. Placebo

Reductions in Inflammatory Lesion Counts at Cycle 6
EE 20 µg/LNG 100 µg (Alesse) vs. Placebo

Reductions in Total Lesion Counts at Cycle 6
EE 20 µg/LNG 100 µg (Alesse) vs. Placebo

How OCs Improve Acne

Primary Dysmenorrhea
Incidence

OC Use in Adolescents
Decreased Dysmenorrhea and Compliance

Primary Dysmenorrhea

How OCs Improve Primary Dysmenorrhea

OC Compliance
A Real Concern with Adolescents

Reported Pill Use vs. Actual Pill Use

Pill-Taking Behaviors by Age

OC Continuation Rates
All Ages

Reasons for OC Discontinuation
All Ages

What Happens When
Women Discontinue OCs

Patients at Risk for BTB

Breakthrough Bleeding in OC New Starts
35 µg EE OC vs. Two 20 µg EE OCs

Breakthrough Bleeding in OC Switchers
35 µg EE OC vs. Two 20 µg EE OCs

OC Formulations and BTB

BTB May Signal Chlamydia

Smoking Affects Rates of BTB

Adolescents’ Anticipated vs. Reported Side Effects
EE 20 µg/LNG 100 µg Formulation

Relative Risk of Estrogen-Related Side Effects
35 µg EE OC vs. Two 20 µg EE OCs

Side Effects of EE 20 µg/LNG 100 µg (Alesse) vs. Placebo: No Significant Difference

Weight Gain Is Not A Trivial Concern for OC Users

Women’s Perceptions About Weight Gain and OCs

Controlled Studies Fail to Show Weight Gain Linked to OC Use

The Press Underreports Studies of OC Benefits

Management of Side Effects
Preventive/Anticipatory Guidance

How to Improve Successful Use of OCs

Improving Successful OC Use
Anticipatory Guidance

Adolescent Counseling

Depo Provera (3-month shot)

Comparison of New
Contraceptive Methods

Contraceptive Implant: Implanon

Implanon Efficacy, Safety and Tolerability

Levonorgestrel Intrauterine System: Mirena

Mirena Cycle Control,
Safety, and Tolerability

Vaginal Ring: NuvaRing

NuvaRing Efficacy

NuvaRing Cycle Control and Tolerability

NuvaRing Compared to OC:
Irregular Bleeding

Contraceptive Patch: Ortho Evra

Ortho Evra Efficacy and Compliance

Ortho Evra Compared to OC:
Breakthrough Bleeding*

Ortho Evra Compared to OC: Adverse Events

Conclusions