Ovarian and Endometrial Cancers and
Low-Dose OCs
n Ovarian cancer
n If protective effect is due to prevention of
“incessant ovulation,” low-dose OCs are likely
protective
n Endometrial cancer
n Data on protective effect indicate no significant
difference between 35 µg and >50 µg EE OCs
Cancer and Steroid Hormone Study/CDC/NICHHD. JAMA. 1987;257:796-800;
Rosenblatt KA et al. Eur J Cancer. 1992;28A:1872-1876.