Emergency Contraception:
History
1960s-70s:  Diethylstilbesterol (DES)
No longer used because of teratogenicity
1974: Yuzpe [pilot study]
100 g ethinyl estradiol (EE) with 1.0 mg dl-
norgestrel; as effective as DES
1977: Yuzpe modified (original dose given twice, 12
hours apart)
1984: Yuzpe available in Europe
LaValleur J.  Obstet Gynecol Clin North Am. 2000;27(4): 817-839.
Ellertson C. Fam Plann Perspect. 1996;28(2):44-48.