RISK ASSESSMENT AND MANAGEMENT
Key question for hazard
identification:
Is it a carcinogen or not?
Scope of the identification problem
Questions in Hazard Identification
Example – methylene chloride (MC) in soil
3. Quantitative
Toxicological
Assessment
Non-Cancer Toxicity
(continued)
Derivation of Reference Dose (RfD)
Example – methylene chloride RfD
Only if the chemical is a
“carcinogen”
Uncertainties in low-dose extrapolation methods
Methylene Chloride Slope Factor
Approaches to benefit analysis
EPA's Seven Cardinal Rules of Risk Communication
Guide to Ineffective Risk Communication
Guide to Ineffective Risk Communication (continued)